J
Julius M. Guccione
Researcher at University of California, San Francisco
Publications - 191
Citations - 6436
Julius M. Guccione is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Heart failure & Finite element method. The author has an hindex of 40, co-authored 178 publications receiving 5573 citations. Previous affiliations of Julius M. Guccione include University of California, San Diego & San Francisco VA Medical Center.
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Journal ArticleDOI
Passive material properties of intact ventricular myocardium determined from a cylindrical model.
TL;DR: The results indicate that torsion, residual stress and material anisotropy associated with the fiber architecture all can act to reduce endocardial stress gradients in the passive left ventricle.
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Finite element stress analysis of left ventricular mechanics in the beating dog heart
TL;DR: There may be significant regional nonhomogeneity of fiber stress in the normal left ventricle associated with regional variations in shape and fiber angle, unlike in the midventricle region that has been studied most fully.
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Theoretical impact of the injection of material into the myocardium: a finite element model simulation.
TL;DR: Simulations indicate that the addition of noncontractile material to a damaged left ventricular wall has important effects on cardiac mechanics, with potentially beneficial reduction of elevated myofiber stresses, as well as confounding changes to clinicalleft ventricular metrics.
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Mechanics of Active Contraction in Cardiac Muscle: Part II—Cylindrical Models of the Systolic Left Ventricle
TL;DR: Models of contracting ventricular myocardium were used to study the effects of different assumptions concerning active tension development on the distributions of stress and strain in the equatorial region of the intact left ventricle during systole.
Journal ArticleDOI
MRI-based finite-element analysis of left ventricular aneurysm
Joseph C. Walker,Mark B. Ratcliffe,Peng Zhang,Arthur W. Wallace,Bahar Fata,Edward W. Hsu,David Saloner,Julius M. Guccione +7 more
TL;DR: Systolic material parameters were determined that enabled FE models to reproduce midwall, systolic myocardial strains from tagged MRI, and contrary to previous hypotheses but consistent with biaxial stretching experiments, active cross-fiber stress development is an integral part of LV systole.