Bio: Jun Cheng is an academic researcher from Guangdong Pharmaceutical University. The author has contributed to research in topics: Vasicine & Peganum harmala. The author has an hindex of 4, co-authored 4 publications receiving 93 citations.
TL;DR: In this article, four new phenolics (17, 18, 22 and 24) along with twenty-five known congeners were isolated and purified from the roots of hairy fig and their structures were elucidated by extensive spectroscopic analysis and chemical degradation.
TL;DR: In this paper, a phytochemical study on the extract of mango leaves resulted in the isolation and identification of 5 benzophenones and 17 flavonoids, including 4 new benzophenone glycosides, elucidated as 4′,6-dihydroxy-4-methoxybenzophenone-2-O-(2)
TL;DR: Results indicated that hairy fig could be served as an anti-inflammatory agent for health products, and exhibited pronounced inhibitory effects on the lipopolysaccharides (LPS) induced nitric oxide (NO) production in murine macrophage RAW 264.7 compared to indomethacin.
TL;DR: A phytochemical study on the methanol extracts from the seeds of Peganum harmala L. led to a new quizonaline alkaloid (S)-vasicinone-1-O-β-d-glucopyranoside, which screened for antiproliferative activity against human gastric cancer cells MCG-803 with MTT method.
TL;DR: Over 200 molecules with a broad range of bioactivities, including antitumor, antimalarial, antibacterial and antifungal, antiparasitic and insecticidal, antiviral, antiplatelet, anti‐inflammatory, herbicidal, antioxidant and other activities, were reviewed.
Abstract: Quinoline and quinazoline alkaloids, two important classes of N-based heterocyclic compounds, have attracted tremendous attention from researchers worldwide since the 19th century. Over the past 200 years, many compounds from these two classes were isolated from natural sources, and most of them and their modified analogs possess significant bioactivities. Quinine and camptothecin are two of the most famous and important quinoline alkaloids, and their discoveries opened new areas in antimalarial and anticancer drug development, respectively. In this review, we survey the literature on bioactive alkaloids from these two classes and highlight research achievements prior to the year 2008 (Part I). Over 200 molecules with a broad range of bioactivities, including antitumor, antimalarial, antibacterial and antifungal, antiparasitic and insecticidal, antiviral, antiplatelet, anti-inflammatory, herbicidal, antioxidant and other activities, were reviewed. This survey should provide new clues or possibilities for the discovery of new and better drugs from the original naturally occurring quinoline and quinazoline alkaloids.
TL;DR: The extensive lethal effect of AgNPs against clinically important pathogens demonstrated that the mango flower mediated AgNPS could be applied as potential antibacterial agent to control the bacterial population in the respective industries.
TL;DR: Harmala plant seeds have a great potential to act as a source of natural colorant for cotton dyeing under the influence of microwave radiation and bio-mordanting has given more excellent rating as compared to chemical mordants.
Abstract: The revival of cultural heritage in a form of natural colorants for textile dyeing is gaining popularity due to their soothing nature and bright shades The present study was conducted to explore the coloring potential of harmala (Peganum harmala) seeds and to improve color strength of dye using microwave radiations followed by a mordanting process The results showed that harmala plant seeds could be an excellent source of natural dyes for cotton dyeing if the irradiated acidified methanolic extract (RE, 4 min) is used to dye un-irradiated fabric (NRC) at 85 °C for 45 min using a dye bath of pH 90 having salt concentration of 7 g/100 mL Alum (1%) as pre-mordants and iron (7%) as post-mordants have improved the color strength in chemical mordanting more than other mordants employed The bio-mordants employed reveal that 10% of acacia as pre-bio-mordants and 7% of acacia as post-bio-mordants are effective amounts to obtain high color strength Suggested ISO standards for colorfastness illustrate that bio-mordanting has given more excellent rating as compared to chemical mordants It is concluded that harmala seeds have a great potential to act as a source of natural colorant for cotton dyeing under the influence of microwave radiation
TL;DR: There is some evidence for extracts' pharmacological effects on Alzheimer's and Parkinson's diseases, cancer, diabetes, hypertension, and drug interaction with standard-of-care medications.
TL;DR: Arab and Islamic traditional plants have emerged as a good source of complementary and alternative medicine in treating cancer and might be promising for new cancer therapeutics with low toxicity and minimal side effects.