J
Jun Furusawa
Researcher at Hokkaido University
Publications - 18
Citations - 252
Jun Furusawa is an academic researcher from Hokkaido University. The author has contributed to research in topics: Radiation therapy & Chemoradiotherapy. The author has an hindex of 8, co-authored 18 publications receiving 226 citations. Previous affiliations of Jun Furusawa include University of Arkansas for Medical Sciences.
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Journal ArticleDOI
Increased Distributional Variance of Mitochondrial DNA Content Associated With Prostate Cancer Cells as Compared With Normal Prostate Cells
Takatsugu Mizumachi,Levan Muskhelishvili,Akihiro Naito,Jun Furusawa,Chun-Yang Fan,Eric R. Siegel,Fred F. Kadlubar,Udaya Kumar,Masahiro Higuchi +8 more
TL;DR: Mitochondria are key organelles for apoptosis, and mitochondrial DNA content can regulate cancer progression, and increases in mtDNA mutations and deletions have been reported in cancer; however, a detailed investigation of mtDNA content in cancer cells has not yet been conducted.
Journal ArticleDOI
Superselective intra-arterial cisplatin infusion and concomitant radiotherapy for maxillary sinus cancer
Akihiro Homma,Tomohiro Sakashita,Daisuke Yoshida,Rikiya Onimaru,Kazuhiko Tsuchiya,Fumiyuki Suzuki,Koichi Yasuda,Hiromitsu Hatakeyama,Jun Furusawa,Takatsugu Mizumachi,Satoshi Kano,Naoya Inamura,Shigenari Taki,Hiroki Shirato,Satoshi Fukuda +14 more
TL;DR: Excellent overall survival and local progression-free rate in SCC-MS patients treated by RADPLAT is shown, with acceptable rates of acute and late toxicity.
Journal ArticleDOI
Superselective arterial cisplatin infusion with concomitant radiation therapy for base of tongue cancer.
Satoshi Kano,Akihiro Homma,Nobuhiko Oridate,Fumiyuki Suzuki,Hiromitsu Hatakeyama,Takatsugu Mizumachi,Jun Furusawa,Tomohiro Sakashita,Daisuke Yoshida,Rikiya Onimaru,Hiroki Shirato,Satoshi Fukuda +11 more
TL;DR: It is found that RADPLAT gave excellent survival rates and organ functions for patients with BOT cancers and that the angiographic technique and patient selection are keys to success.
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Comparison of acute toxicities associated with cetuximab-based bioradiotherapy and platinum-based chemoradiotherapy for head and neck squamous cell carcinomas: A single-institution retrospective study in Japan.
Tomohiro Sakashita,Akihiro Homma,Hiromitsu Hatakeyama,Jun Furusawa,Satoshi Kano,Takatsugu Mizumachi,Satoshi Iizuka,Rikiya Onimaru,Kazuhiko Tsuchiya,Koichi Yasuda,Hiroki Shirato,Satoshi Fukuda +11 more
TL;DR: The BRT group had a higher incidence of Grade ≥ 3 radiation dermatitis than did the CRT group and the safety of cetuximab-based BRT in comparison with platinum-based CRT is currently under investigation.
Journal ArticleDOI
Distinct epigenetic profiling in head and neck squamous cell carcinoma stem cells.
Jun Furusawa,Haihong Zhang,Emre Vural,Annjanette Stone,Satoshi Fukuda,Nobuhiko Oridate,Hong Fang,Yanbin Ye,James Y. Suen,Chun-Yang Fan +9 more
TL;DR: A unique epigenetic profile consisting of 17 hypomethylated and 9 hypermethylated genes was seen in HNSCC CSCs, which may be critically required in maintaining the stemness or pluripotency of C SCs and may represent novel molecular targets for anticancer therapies aimed at eradicating CSCS in H NSCC.