J
Jun Hirabayashi
Researcher at National Institute of Advanced Industrial Science and Technology
Publications - 273
Citations - 16685
Jun Hirabayashi is an academic researcher from National Institute of Advanced Industrial Science and Technology. The author has contributed to research in topics: Lectin & Galectin. The author has an hindex of 66, co-authored 270 publications receiving 15579 citations. Previous affiliations of Jun Hirabayashi include Teikyo University & Kagawa University.
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Journal ArticleDOI
Galectins: a family of animal beta-galactoside-binding lectins.
Samuel H. Barondes,Vincent Castronovo,Douglas N.W. Cooper,Richard D. Cummings,Kurt Drickamer,Ten Felzi,Michael A. Gitt,Jun Hirabayashi,Colin Hughes,Ken-ichi Kasai,Hakon Leffler,Fu-Tong Liu,Reuben Lotan,Arthur M. Mercurio,Michel Monsigny,Shiv Pillai,Françoise Poirer,Avraham Raz,Peter W.J. Rigby,James M. Rini,John L. Wang +20 more
Journal ArticleDOI
Oligosaccharide specificity of galectins: a search by frontal affinity chromatography.
Jun Hirabayashi,Tomomi Hashidate,Yoichiro Arata,Nozomu Nishi,Takanori Nakamura,Mitsuomi Hirashima,Tadasu Urashima,Toshihiko Oka,Masamitsu Futai,Werner E.G. Müller,Fumio Yagi,Ken-ichi Kasai +11 more
TL;DR: In this paper, a frontal affinity chromatography (FAC) was used to quantitatively analyze the interactions at 20 °C between 13 galectins including 16 CRDs originating from mammals, chick, nematode, sponge, and mushroom, with 41 pyridylaminated (PA) oligosaccharides.
Journal ArticleDOI
Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins
Hiroyuki Kaji,Haruna Saito,Yoshio Yamauchi,Takashi Shinkawa,Masato Taoka,Jun Hirabayashi,Ken-ichi Kasai,Nobuhiro Takahashi,Nobuhiro Takahashi,Toshiaki Isobe,Toshiaki Isobe +10 more
TL;DR: The approach, termed isotope-coded glycosylation-site-specific tagging (IGOT), is based on the lectin column–mediated affinity capture of a set of glycopeptides generated by tryptic digestion of protein mixtures, followed by peptide-N-glycosidase–mediated incorporation of a stable isotope tag, 18O, specifically into the N-glyCosylation site.
Journal ArticleDOI
The family of metazoan metal-independent β-galactoside-binding lectins: structure, function and molecular evolution
Jun Hirabayashi,Ken-ichi Kasai +1 more
TL;DR: It appears that beta-galactoside-binding lectins and some non-lectin proteins form a superfamily whose members are widely distributed from vertebrates to invertebrates and a consideration of molecular evolution suggests that lectins belonging to this family probably existed in the Precambrian era.
Journal ArticleDOI
Evanescent-field fluorescence-assisted lectin microarray: a new strategy for glycan profiling.
Atsushi Kuno,Noboru Uchiyama,Shiori Koseki-Kuno,Youji Ebe,Seigo Takashima,Masao Yamada,Jun Hirabayashi +6 more
TL;DR: A new microarray procedure based on an evanescent-field fluorescence-detection principle that allows sensitive, real-time observation of multiple lectin-carbohydrate interactions under equilibrium conditions is described, which should contribute to creation of a new paradigm for glycomics.