J
Jun Ohashi
Researcher at University of Tokyo
Publications - 241
Citations - 8690
Jun Ohashi is an academic researcher from University of Tokyo. The author has contributed to research in topics: Single-nucleotide polymorphism & Population. The author has an hindex of 51, co-authored 233 publications receiving 7938 citations. Previous affiliations of Jun Ohashi include Cornell University & University of Tsukuba.
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Journal ArticleDOI
Mapping human genetic diversity in Asia
Mahmood Ameen Abdulla,Ikhlak Ahmed,Anunchai Assawamakin,Anunchai Assawamakin,Jong Bhak,Samir K. Brahmachari,Gayvelline C. Calacal,Amit Kumar Chaurasia,Chien-Hsiun Chen,Jieming Chen,Yuan-Tsong Chen,Jiayou Chu,Eva Maria Cutiongco-de la Paz,Maria Corazon A. De Ungria,Frederick C. Delfin,Juli Edo,Suthat Fuchareon,Ho Ghang,Takashi Gojobori,Junsong Han,Sheng Feng Ho,Boon Peng Hoh,Wei Huang,Hidetoshi Inoko,Pankaj Jha,Timothy A. Jinam,Li Jin,Jongsun Jung,Daoroong Kangwanpong,Jatupol Kampuansai,Giulia C. Kennedy,Preeti Khurana,Hyung Lae Kim,Kwangjoong Kim,Sangsoo Kim,Woo Yeon Kim,Kuchan Kimm,Ryosuke Kimura,Tomohiro Koike,Supasak Kulawonganunchai,Vikrant Kumar,Poh San Lai,Jong-Young Lee,Sunghoon Lee,Edison T. Liu,Partha P. Majumder,Kiran Kumar Mandapati,Sangkot Marzuki,Wayne Mitchell,Wayne Mitchell,Mitali Mukerji,Kenji Naritomi,Chumpol Ngamphiw,Norio Niikawa,Nao Nishida,Bermseok Oh,Sangho Oh,Jun Ohashi,Akira Oka,Rick Twee-Hee Ong,Carmencita Padilla,Prasit Palittapongarnpim,Henry B. Perdigon,Maude E. Phipps,Maude E. Phipps,Eileen Png,Yoshiyuki Sakaki,Jazelyn M. Salvador,Yuliana Sandraling,Vinod Scaria,Mark Seielstad,Mohd Ros Sidek,Amit Sinha,Metawee Srikummool,Herawati Sudoyo,Sumio Sugano,Helena Suryadi,Yoshiyuki Suzuki,Kristina A. Tabbada,Adrian Tan,Katsushi Tokunaga,Sissades Tongsima,Lilian P. Villamor,Eric Wang,Ying Wang,Haifeng Wang,Jer-Yuarn Wu,Huasheng Xiao,Shuhua Xu,Jin Ok Yang,Yin Yao Shugart,Hyang Sook Yoo,Wentao Yuan,Guoping Zhao,Bin Alwi Zilfalil +94 more
TL;DR: The results suggest that there may have been a single major migration of people into Asia and a subsequent south-to-north migration across the continent, and that genetic ancestry is strongly correlated with linguistic affiliations as well as geography.
Journal ArticleDOI
A Practical Genome Scan for Population-Specific Strong Selective Sweeps That Have Reached Fixation
TL;DR: This study confirms strong positive selection on genes previously reported to be associated with specific phenotypes, and identifies other candidates that are likely to contribute to phenotypic differences between human populations.
Journal ArticleDOI
A scan for genetic determinants of human hair morphology: EDAR is associated with Asian hair thickness
Akihiro Fujimoto,Ryosuke Kimura,Jun Ohashi,Kazuya Omi,Rika Yuliwulandari,Lilian Batubara,Mohammad Syamsul Mustofa,Urai Samakkarn,Wannapa Settheetham-Ishida,Takafumi Ishida,Yasuyuki Morishita,Takuro Furusawa,Minato Nakazawa,Ryutaro Ohtsuka,Katsushi Tokunaga +14 more
TL;DR: It is concluded that EDAR is a major genetic determinant of Asian hair thickness and the 1540C allele spread through Asian populations due to recent positive selection.
Journal ArticleDOI
The G/G Genotype of a Resistin Single-Nucleotide Polymorphism at −420 Increases Type 2 Diabetes Mellitus Susceptibility by Inducing Promoter Activity through Specific Binding of Sp1/3
Haruhiko Osawa,Kazuya Yamada,Kazuya Yamada,Hiroshi Onuma,Akiko Murakami,Masaaki Ochi,Hiroko Kawata,Tatsuya Nishimiya,Toshiyuki Niiya,Ikki Shimizu,Wataru Nishida,Mitsuru Hashiramoto,Azuma Kanatsuka,Yasuhisa Fujii,Jun Ohashi,Hideichi Makino +15 more
TL;DR: It is found that the -420G/G genotype was associated with type 2 diabetes mellitus (T2DM) and could accelerate the onset of disease by 4.9 years, and fasting serum resistin levels were higher in subjects with T2DM who carried the - 420G/ G genotype.
Journal ArticleDOI
Brain Cannabinoid CB2 Receptor in Schizophrenia
Hiroki Ishiguro,Yasue Horiuchi,Maya Ishikawa,Minori Koga,Keiko Imai,Yoshimi Suzuki,Miyuki Morikawa,Toshiya Inada,Yuichiro Watanabe,Makoto Takahashi,Toshiyuki Someya,Hiroshi Ujike,Nakao Iwata,Norio Ozaki,Emmanuel S. Onaivi,Hiroshi Kunugi,Tsukasa Sasaki,Masanari Itokawa,Makoto Arai,Kazuhiro Niizato,Shyuji Iritani,Izumi Naka,Jun Ohashi,Akiyoshi Kakita,Hitoshi Takahashi,Hiroyuki Nawa,Tadao Arinami +26 more
TL;DR: Findings indicate an increased risk of schizophrenia for people with low CB2 receptor function, as well as nominally significant associations between schizophrenia and two SNPs.