J
Junfeng Guo
Researcher at Chinese Center for Disease Control and Prevention
Publications - 49
Citations - 3195
Junfeng Guo is an academic researcher from Chinese Center for Disease Control and Prevention. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 14, co-authored 43 publications receiving 2959 citations. Previous affiliations of Junfeng Guo include Centers for Disease Control and Prevention & National Health and Family Planning Commission.
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Journal ArticleDOI
Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus
Rongbao Gao,Bin Cao,Yunwen Hu,Zijian Feng,Dayan Wang,Wanfu Hu,Jian Chen,Zhijun Jie,Haibo Qiu,Ke Xu,Xuewei Xu,Hongzhou Lu,Wenfei Zhu,Zhancheng Gao,Nijuan Xiang,Yinzhong Shen,Zebao He,Y. Gu,Zhiyong Zhang,Yi Yang,Xiang Zhao,Lei Zhou,Xiaodan Li,Shumei Zou,Ye Zhang,Xiyan Li,Lei Yang,Junfeng Guo,Jie Dong,Qun Li,Libo Dong,Yun Zhu,Tian Bai,Shiwen Wang,Pei Hao,Weizhong Yang,Yanping Zhang,Jun Han,Hongjie Yu,Dexin Li,George F. Gao,Guizhen Wu,Yu Wang,Zhenghong Yuan,Yuelong Shu +44 more
TL;DR: Novel reassortant H7N9 viruses were associated with severe and fatal respiratory disease in three patients, and all three patients died.
Journal ArticleDOI
Biological features of novel avian influenza A (H7N9) virus
Jiangfang Zhou,Dayan Wang,Rongbao Gao,Baihui Zhao,Jingdong Song,Xian Qi,Yanjun Zhang,Yonglin Shi,Lei Yang,Wenfei Zhu,Tian Bai,Kun Qin,Yu Lan,Shumei Zou,Junfeng Guo,Jie Dong,Libo Dong,Ye Zhang,Hejiang Wei,Xiaodan Li,Jian Lu,Liqi Liu,Xiang Zhao,Xiyan Li,Weijuan Huang,Le-ying Wen,Hong Bo,Li Xin,Y. Chen,Cuilin Xu,Yuquan Pei,Yue Yang,Xiaodong Zhang,Shiwen Wang,Zijian Feng,Jun Han,Weizhong Yang,George F. Gao,Guizhen Wu,Dexin Li,Yu Wang,Yuelong Shu +41 more
TL;DR: It is shown that the emerging H7N9 avian influenza virus poses a potentially high risk to humans, and current seasonal vaccination could not provide protection.
Journal ArticleDOI
Two Outbreak Sources of Influenza A (H7N9) Viruses Have Been Established in China
Dayan Wang,Lei Yang,Wenfei Zhu,Ye Zhang,Shumei Zou,Hong Bo,Rongbao Gao,Jie Dong,Weijuan Huang,Junfeng Guo,Zi Li,Xiang Zhao,Xiaodan Li,Li Xin,Jianfang Zhou,Tao Chen,Libo Dong,Hejiang Wei,Xiyan Li,Liqi Liu,Jing Tang,Yu Lan,Jing Yang,Yuelong Shu +23 more
TL;DR: Both sources in the Yangtze River Delta region and the Pearl RiverDelta region have been established and found to be responsible for the H7N9 outbreaks in mainland China, posing a long-term threat of H7n9 infection in humans.
Journal ArticleDOI
Genetic tuning of the novel avian influenza A(H7N9) virus during interspecies transmission, China, 2013.
Dayan Wang,Limei Yang,Rongbao Gao,Xiaodong Zhang,Y Tan,Aiping Wu,Wenfei Zhu,Jianfang Zhou,Shumei Zou,Xiyan Li,Y Sun,Ye Zhang,Y Liu,T Liu,Ying Xiong,J Xu,L Chen,Y Weng,X Qi,Junfeng Guo,Xiaodan Li,Jinming Dong,Weijuan Huang,Lixin Dong,Xiang Zhao,Liqi Liu,Jian Lu,Yu Lan,Hua Wei,Li Xin,Y. Chen,Cuiling Xu,Tao Chen,Yun Zhu,Tao Jiang,Zijian Feng,Weizhong Yang,Yu Wang,Hongbo Zhu,Yi Guan,George F. Gao,Dexin Li,Jun Han,Shiwen Wang,Guizhen Wu,Yuelong Shu +45 more
TL;DR: A genetic tuning procedure with continuous amino acid substitutions and reassorting that mediates host adaptation and interspecies transmission is proposed and may create opportunities for further adaptation of influenza A(H7N9) and its potential to cause a pandemic.
Journal ArticleDOI
Novel Avian-Origin Human Influenza A(H7N9) Can Be Transmitted Between Ferrets via Respiratory Droplets
Lili Xu,Linlin Bao,Wei Deng,Libo Dong,Hua Zhu,Ting Chen,Qi Lv,Fengdi Li,Jing Yuan,Zhiguang Xiang,Kai Gao,Yanfeng Xu,Lan Huang,Yanhong Li,Jiangning Liu,Yanfeng Yao,Pin Yu,Xiyan Li,Weijuan Huang,Xiang Zhao,Yu Lan,Junfeng Guo,Weidong Yong,Qiang Wei,Honglin Chen,Lianfeng Zhang,Chuan Qin +26 more
TL;DR: It is emphasized that avian-origin influenza A(H7N9) can be transmitted between mammals, highlighting its potential for human-to-human transmissibility.