J
Junghuei Chen
Researcher at University of Delaware
Publications - 64
Citations - 2915
Junghuei Chen is an academic researcher from University of Delaware. The author has contributed to research in topics: DNA & DNA nanotechnology. The author has an hindex of 24, co-authored 64 publications receiving 2772 citations. Previous affiliations of Junghuei Chen include University of California, Berkeley & University at Albany, SUNY.
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Journal ArticleDOI
Synthesis from DNA of a molecule with the connectivity of a cube
Junghuei Chen,Nadrian C. Seeman +1 more
TL;DR: This work reports the construction from DNA of a covalently closed cube-like molecular complex containing twelve equal-length double-helical edges arranged about eight vertices, the first construction of a closed polyhedral object from DNA.
Journal ArticleDOI
The topology of the kinetoplast DNA network.
TL;DR: It is concluded that each minicircle is linked on average to three other minicircles of the Crithidia fasciculata network, which has implications for the assembly, structure, and function of kDNA networks.
Journal ArticleDOI
Cationic peptide antimicrobials induce selective transcription of micF and osmY in Escherichia coli.
Joon-Taek Oh,Yolanda Cajal,Ewa M. Skowronska,Shimshon Belkin,Junghuei Chen,Tina K. Van Dyk,Myron Sasser,Mahendra Kumar Jain +7 more
TL;DR: Results show that the antibacterial cationic peptides induce stasis in the early growth phase, and the transcriptional efficacy of antibacterial peptides correlates with their minimum inhibitory concentration, and also with their ability to mediate direct exchange of phospholipids between vesicles.
Book ChapterDOI
A PCR-based Protocol for In Vitro Selection of Non-crosshybridizing Oligonucleotides
TL;DR: A modified version of PCR that selects non-crosshybridizing oligon nucleotides was designed and tested and it was confirmed that the PCR-based protocol did amplify maximally mismatched oligonucleotides selectively over those that were more closely matched.
Journal ArticleDOI
New motifs in DNA nanotechnology
Nadrian C. Seeman,Hui Wang,Xiaoping Yang,Furong Liu,Chengde Mao,Weiqiong Sun,Lisa A. Wenzler,Zhiyong Shen,Ruojie Sha,Hao Yan,Man Hoi Wong,Phiset Sa-Ardyen,Bing Liu,Hangxia Qiu,Xiaojun Li,Jing Qi,Shou Ming Du,Yuwen Zhang,John E. Mueller,Tsu Ju Fu,Yinli Wang,Junghuei Chen +21 more
TL;DR: It is discovered that DNA double crossover molecules can provide this capability, and these components are incorporated in DNA assemblies that use this rigidity to achieve control on the geometrical level, as well as on the topological level.