J
Juraj Galeta
Researcher at Academy of Sciences of the Czech Republic
Publications - 24
Citations - 224
Juraj Galeta is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Cycloaddition & Tetrazine. The author has an hindex of 8, co-authored 22 publications receiving 158 citations. Previous affiliations of Juraj Galeta include Masaryk University.
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Journal ArticleDOI
Photochemical Formation of Dibenzosilacyclohept-4-yne for Cu-Free Click Chemistry with Azides and 1,2,4,5-Tetrazines
TL;DR: Steady-state irradiation, kinetic, and transient absorption spectroscopy studies revealed that strained alkyne 3 is rapidly (<5 ns) and efficientlyPhotochemical generation of dibenzosilacyclohept-4-yne 3 from the corresponding cyclopropenone 1 and its copper-free click reactions are reported.
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Design and Synthesis of Aza-Bicyclononene Dienophiles for Rapid Fluorogenic Ligations.
Sebastian J. Siegl,Arcadio Vázquez,Rastislav Dzijak,Martin Dračínský,Juraj Galeta,Robert Rampmaier,Blanka Klepetářová,Milan Vrabel +7 more
TL;DR: The design and synthesis of conformationally-strained aziridine-fused trans-cyclooctene (aza-TCO) dienophiles, which lead to the formation of fluorescent products in tetrazine ligations without the need for attachment of an extra fluorophore moiety are presented.
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A Systematic Study of Coumarin-Tetrazine Light-Up Probes for Bioorthogonal Fluorescence Imaging.
TL;DR: The best compound identified in this study showed excellent performance in live cell‐labeling experiments and enabled no‐wash fluorogenic imaging on a timescale of seconds.
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Dihydropyrrolo[1,2-b]pyrazoles: withasomnine and related compounds
TL;DR: In this paper, a complex methodology involving the preparation of substituted DPPs focusing on withasomnine and the synthesis of several structurally related compounds was presented. But the complexity of the methodology was not addressed.
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An Extended Approach for the Development of Fluorogenic trans-Cyclooctene-Tetrazine Cycloadditions.
Sebastian J. Siegl,Juraj Galeta,Rastislav Dzijak,Arcadio Vázquez,Miguel Del Río‐Villanueva,Martin Dračínský,Milan Vrabel +6 more
TL;DR: It is shown that even the reaction intermediates formed in iEDDA cycloaddition can lead to the formation of new types of fluorophores.