J
Justin L. Sonnenburg
Researcher at Stanford University
Publications - 167
Citations - 24459
Justin L. Sonnenburg is an academic researcher from Stanford University. The author has contributed to research in topics: Gut flora & Microbiome. The author has an hindex of 54, co-authored 147 publications receiving 17651 citations. Previous affiliations of Justin L. Sonnenburg include University of California, Davis & Washington University in St. Louis.
Papers
More filters
Journal ArticleDOI
Host-Bacterial Mutualism in the Human Intestine
TL;DR: New studies are revealing how the gut microbiota has coevolved with us and how it manipulates and complements the authors' biology in ways that are mutually beneficial.
Journal ArticleDOI
Diet–microbiota interactions as moderators of human metabolism
TL;DR: A body of knowledge is accumulating that points to the gut microbiota as a mediator of dietary impact on the host metabolic status and the prospect of therapeutic interventions such as personalized nutrition.
Journal ArticleDOI
Diet-induced extinctions in the gut microbiota compound over generations
Erica D. Sonnenburg,Samuel A. Smits,Mikhail Tikhonov,Steven K. Higginbottom,Ned S. Wingreen,Justin L. Sonnenburg +5 more
TL;DR: It is shown that changes in the microbiota of mice consuming a low-MAC diet and harbouring a human microbiota are largely reversible within a single generation, and that taxa driven to low abundance when dietary MACs are scarce are inefficiently transferred to the next generation and are at increased risk of becoming extinct within an isolated population.
Journal ArticleDOI
Glycan Foraging in Vivo by an Intestine-Adapted Bacterial Symbiont
Justin L. Sonnenburg,Jian Xu,Douglas D. Leip,Chien-Huan Chen,Benjamin P. Westover,Jeremy Weatherford,Jeremy Buhler,Jeffrey I. Gordon +7 more
TL;DR: It is found that Bacteroides thetaiotaomicron bacteria assembled on food particles and mucus, selectively induced outer-membrane polysaccharide-binding proteins and glycoside hydrolases, prioritized the consumption of liberated hexose sugars, and revealed a capacity to turn to host mucus glycans whenpolysaccharides were absent from the diet.
Journal ArticleDOI
Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens
Katharine M. Ng,Jessica A. Ferreyra,Steven K. Higginbottom,Jonathan B. Lynch,Purna C. Kashyap,Purna C. Kashyap,Smita Gopinath,Natasha Naidu,Biswa Choudhury,Bart C. Weimer,Denise M. Monack,Justin L. Sonnenburg +11 more
TL;DR: The data show that antibiotic-induced disruption of the resident microbiota and subsequent alteration in mucosal carbohydrate availability are exploited by these two distantly related enteric pathogens in a similar manner, which suggests new therapeutic approaches for preventing diseases caused by antibiotic-associated pathogens.