Author
K.A.L. Darvall
Other affiliations: Musgrove Park Hospital, North Devon District Hospital
Bio: K.A.L. Darvall is an academic researcher from University of Birmingham. The author has contributed to research in topics: Sclerotherapy & Varicose veins. The author has an hindex of 16, co-authored 24 publications receiving 911 citations. Previous affiliations of K.A.L. Darvall include Musgrove Park Hospital & North Devon District Hospital.
Papers
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TL;DR: Obesity appears to be associated with thrombosis via several mechanisms that are all improved by weight loss, including the actions of so-called adipocytokines from adipose tissue.
285 citations
TL;DR: UGFS for CEAP 2-6 SVR is associated with a low complication and retreatment rate, however, as patients are at risk of developing recurrent and new SVR they should be kept under review.
81 citations
TL;DR: Physical and mental HRQL is significantly worse in VV patients with lower limb symptoms irrespective of the clinical stage of disease, confirming that VV are not primarily a cosmetic problem and that NHS rationing of treatment to those with CEAP C4-6 disease excludes many patients who would benefit from intervention in terms of HRQL.
68 citations
TL;DR: Re-recurrence at 12 months is superior to that reported after redo GSV surgery, similar to that observed following other minimally-invasive techniques and, when it occurs, is effectively and simply treated by a single further session of UGFS.
67 citations
TL;DR: Healing rates following UGFS for CVU are comparable to those reported after surgery but recurrence may be lower and UG FS is a safe, clinically effective and, thus, highly attractive minimally invasive alternative to surgery in patients with C5 and C6 disease.
58 citations
Cited by
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TL;DR: Photoplethysmography is a simple and low-cost optical technique that can be used to detect blood volume changes in the microvascular bed of tissue and is often used non-invasively to make measurements at the skin surface.
Abstract: Photoplethysmography (PPG) is a simple and low-cost optical technique that can be used to detect blood volume changes in the microvascular bed of tissue. It is often used non-invasively to make measurements at the skin surface. The PPG waveform comprises a pulsatile ('AC') physiological waveform attributed to cardiac synchronous changes in the blood volume with each heart beat, and is superimposed on a slowly varying ('DC') baseline with various lower frequency components attributed to respiration, sympathetic nervous system activity and thermoregulation. Although the origins of the components of the PPG signal are not fully understood, it is generally accepted that they can provide valuable information about the cardiovascular system. There has been a resurgence of interest in the technique in recent years, driven by the demand for low cost, simple and portable technology for the primary care and community based clinical settings, the wide availability of low cost and small semiconductor components, and the advancement of computer-based pulse wave analysis techniques. The PPG technology has been used in a wide range of commercially available medical devices for measuring oxygen saturation, blood pressure and cardiac output, assessing autonomic function and also detecting peripheral vascular disease. The introductory sections of the topical review describe the basic principle of operation and interaction of light with tissue, early and recent history of PPG, instrumentation, measurement protocol, and pulse wave analysis. The review then focuses on the applications of PPG in clinical physiological measurements, including clinical physiological monitoring, vascular assessment and autonomic function.
2,836 citations
TL;DR: The Society for Vascular Surgery and the American Venous Forum have developed clinical practice guidelines for the care of patients with varicose veins of the lower limbs and pelvis, including recommendations on the management of superficial and perforating vein incompetence in patients with associated, more advanced chronic venous diseases.
1,162 citations
TL;DR: In this article, the management of chronic venous disease is addressed in the Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS) and the ESCV guidelines are presented.
656 citations
Tufts University1, University of Alabama at Birmingham2, University of Michigan3, Indiana University4, Lund University5, University of Illinois at Chicago6, Uniformed Services University of the Health Sciences7, Mayo Clinic8, University of North Carolina at Chapel Hill9, Oregon Health & Science University10, Medical University of Vienna11, University of Texas Health Science Center at San Antonio12, Harvard University13, Duke University14
TL;DR: Thomas F. O'Donnell, MD, Marc A. Passman and Peter K. Gloviczki as mentioned in this paper, MD, PhD, Bo G. Eklof et al.
497 citations