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K. B. Sharpless

Bio: K. B. Sharpless is an academic researcher. The author has contributed to research in topics: Absolute configuration & Sodium periodate. The author has an hindex of 1, co-authored 1 publications receiving 134 citations.

Papers
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TL;DR: In this article, the system of Ti(O-iPr) 4, tortrate de diethyle et hydroperoxyde de t-butyle: obtention d'oxirannepropanol est oxyde en acide oxiranneacetique.
Abstract: Epoxydation d'alcene-3ols-1 par le systeme Ti(O-iPr) 4 , tortrate de diethyle et hydroperoxyde de t-butyle: obtention d'oxirannepropanols. L'oxirannepropanol est oxyde en acide oxiranneacetique puis traite par NH 4 OH pour obtenir l'acide (−)-amino-4 hydroxy-3 butyrique

134 citations


Cited by
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Journal ArticleDOI
TL;DR: This paper presents results of aalysis experiment conducted at the Dalian Institute of Chemical Physics of Chinese Academy of Sciences (Dalian 116023) and Jingmen Technological College (Jingmen 448000) using gas chromatography for the recovery of Na6(CO3) from Na2SO4.
Abstract: Laboratory for Advanced Materials and New Catalysis, School of Chemistry and Materials Science, Hubei University, Wuhan 430062, China,Laboratory of Natural Gas Utilization and Applied Catalysis, Dalian Institute of Chemical Physics of Chinese Academy of Sciences, Dalian 116023,China, and Jingmen Technological College, Jingmen 448000, ChinaReceived June 30, 2004

864 citations

Journal ArticleDOI
TL;DR: The chiral epoxidation of olefins with per&d8 and monooxygenases with cytochromes P-450 shows good chiral recognition ability, and the chiral reagents used in this synthesis show low levels of chiral specificity.

251 citations

Journal ArticleDOI
TL;DR: The formation by P450BM-3 of a single oxidant species capable of olefinic bond epoxidation and sp3 carbon hydroxylation is proposed, demonstrating that product chemistry and catalytic outcome are critically dependent on active site spatial coordinates responsible for substrate binding and productive orientation between heme-bound active oxygen and acceptor carbon bond(s).

198 citations

Journal ArticleDOI
TL;DR: An overview of synthetic approaches to linear and cyclic chiral γ-amino acids and derivatives is presented in this article, where data on the practical applications of these acids are also discussed.
Abstract: γ-Amino acids have attracted considerable attention as biologically active compounds in the central nervous system (CNS) of mammals. Over the last few years, significant interest in the stereoselective synthesis and practical application of linear and cyclic chiral γ-amino acids in the synthesis and design of α,β- and β,γ-hybrid peptides with definite secondary structures and design of nanotubes has been reported, thus demonstrating the theoretical interest and the practical importance of γ-amino acids. An overview of synthetic approaches to linear and cyclic chiral γ-amino acids and derivatives is presented. Data on the practical applications of γ-amino acids are also discussed.

185 citations