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K. J. Schjoedt

Researcher at Steno Diabetes Center

Publications -  17
Citations -  1607

K. J. Schjoedt is an academic researcher from Steno Diabetes Center. The author has contributed to research in topics: Diabetic nephropathy & Renal function. The author has an hindex of 13, co-authored 17 publications receiving 1519 citations. Previous affiliations of K. J. Schjoedt include Erasmus University Rotterdam & Health Science University.

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Beneficial Effects of Adding Spironolactone to Recommended Antihypertensive Treatment in Diabetic Nephropathy: A randomized, double-masked, cross-over study

TL;DR: It is suggested that spironolactone safely adds to the reno- and cardiovascular protective benefits of treatment with maximally recommended doses of ACE inhibitor and ARB by reducing albuminuria and blood pressure in type 2 diabetic patients with nephropathy.
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Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria

TL;DR: Ultrahigh dosing of irbesartan (900 mg once daily) is generally safe and offers additional renoprotection independent of changes in systemic blood pressure and GFR in comparison to the currently recommended dose of 300 mg.
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Aldosterone escape during blockade of the renin-angiotensin-aldosterone system in diabetic nephropathy is associated with enhanced decline in glomerular filtration rate.

TL;DR: The data suggest that aldosterone escape during long-term blockade of the renin–angiotensin–aldosterone system is associated with an enhanced decline in GFR in patients with type 1 diabetes and diabetic nephropathy.
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Beneficial impact of spironolactone on nephrotic range albuminuria in diabetic nephropathy.

TL;DR: It is suggested that spironolactone treatment on top of recommended renoprotective treatment including maximal renin-angiotensin system blockade may offer additional renoprotsection in patients with diabetic nephropathy and nephrotic range albuminuria.