K
K. M. Muraleedharan
Researcher at Indian Institute of Technology Madras
Publications - 49
Citations - 802
K. M. Muraleedharan is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topics: Artemisinin & Carboxylic acid. The author has an hindex of 12, co-authored 47 publications receiving 751 citations. Previous affiliations of K. M. Muraleedharan include University of Mississippi & Indian Institute of Chemical Technology.
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Journal ArticleDOI
Unique assemblies of alternating positively and negatively charged layers, directed by hydrogen bonds, ionic interactions, and π-stacking in the crystal structures of complexes between mellitic acid (benzenehexacarboxylic acid) and five planar aromatic bases
Isabella L. Karle,Richard Gilardi,Ch. Chandrashekhar Rao,K. M. Muraleedharan,Subramania Ranganathan +4 more
TL;DR: In this article, the authors show that the planar base ions are generally arranged in stacks in which the components range from being parallel, with interplanar separations of 3.5 A, to having a considerable tilt with respect to each other with nearest interplanars separation of atoms greater than 3.9 A. These geometric characteristics are reflected in the color of the crystals.
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Highly chemoselective esterification reactions and Boc/THP/TBDMS discriminating deprotections under samarium(III) catalysis.
TL;DR: The usefulness of SmCl(3) as an excellent catalyst for chemoselective esterifications and selective removal of acid sensitive protecting groups such as Boc, THP, and TBDMS in the presence of one another is demonstrated through suitable examples.
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Biocatalysis of the Antimalarial Artemisinin by Mucor ramannianus. Strains
Igor A. Parshikov,Bruhaspathy Miriyala,K. M. Muraleedharan,Anuradha Illendula,Mitchell A. Avery,John S. Williamson +5 more
TL;DR: Biocatalysis of artemisinin by different strains of Mucor ramannianus.
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The design and synthesis of redox core-alpha amino acid composites based on thiol-disulfide exchange mechanism and a comparative study of their zinc abstraction potential from [CCXX] boxes in proteins
Subramania Ranganathan,Subramania Ranganathan,K. M. Muraleedharan,Parimal K. Bharadwaj,Dipankar Chatterji,Isabella L. Karle +5 more
TL;DR: In this paper, the authors showed that the removal of the exchangeable zinc atoms in the [CCXX] boxes of E. coli RNA polymerase can be achieved by using thioldisulfide exchange-having as a control.
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Hydroxylation of 10-deoxoartemisinin by Cunninghamella elegans.
Igor A. Parshikov,K. M. Muraleedharan,Bruhaspathy Miriyala,Mitchell A. Avery,John S. Williamson +4 more
TL;DR: The metabolites 2 and 4 retained an intact peroxide group and are therefore useful scaffolds for synthetic modification in the search for new antimalarial agents.