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Kaibo Zheng

Bio: Kaibo Zheng is an academic researcher from China Three Gorges University. The author has contributed to research in topics: Fluorescence & Chemistry. The author has an hindex of 13, co-authored 36 publications receiving 499 citations. Previous affiliations of Kaibo Zheng include Guangxi University for Nationalities.

Papers
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Journal ArticleDOI
TL;DR: In this paper, the most significant developments in fluorescent probes for the detection of the carbonyl species formaldehyde, carbon monoxide and phosgene in recent years, with a special emphasis on their mechanisms and applications.

133 citations

Journal ArticleDOI
TL;DR: In this paper, a ratiometric fluorescent probe (HBT-FA) based on aza-Cope reaction was designed and synthesized, which showed high selectivity and ratiometric fluorescence response to FA.
Abstract: Developing simple and selective methods for formaldehyde (FA) detection are of great interest, because FA is not only an environmental pollutant, but also an endogenous bioactive molecule. Herein, a new ratiometric fluorescent probe (HBT-FA) based on aza-Cope reaction was designed and synthesized, which showed high selectivity and ratiometric fluorescence response to FA. Furthermore, the probe could detect FA in various medium, such as aqueous solution, serum and air.

98 citations

Journal ArticleDOI
TL;DR: In this paper, a small molecule ratiometric fluorescent probe P-Hg was designed and synthesized for monitoring Hg2+ based on ESIPT/ICT mechanisms and its structure was confirmed by X-ray, NMR and HRMS spectrum.
Abstract: Sensitive detecting of Hg2+ in the ecological environment and biological systems has become essential because these contaminants can cause serious health hazard and environmental pollution problem. Herein, we design and synthesize a new small molecule ratiometric fluorescent probe P-Hg for monitoring Hg2+ based on ESIPT/ICT mechanisms. The structure of probe P-Hg was confirmed by X-ray, NMR and HRMS spectrum. Significantly, the probe P-Hg exhibits desirable properties such as high sensitivity, high selectivity and good linearity of the concentrations of Hg2+ (0–35 μM) with a low detection limit (S/N = 3) of 5.8 nM. Furthermore, the detecting mechanism was proved by HRMS,1H NMR.

79 citations

Journal ArticleDOI
TL;DR: In this article, a correlation has been established between the different synthetic strategies and catalytic activities, and the correlation has also been established that the different strategies have different catalytic activity.
Abstract: Earth-abundant nanocatalysts are actively searched to replace expensive noble metal catalysts for a number of essential processes. Here, Cu catalysts have been designed based on manganese oxide octahedral molecular sieve (OMS-2) supports to optimize the catalytic activity in nitrophenol reduction, CuAAC click reaction and terminal alkyne homocoupling. A correlation has been established between the different synthetic strategies and catalytic activities. CuOx/OMS-2 has also been found an efficient catalyst for the homocoupling of terminal alkynes, click reaction and the reduction of 4-nitrophenol, 2,4-dinitrophenol and 4-nitrobenzene diazo tetrafluoroborate with high activity, whereas Cu-OMS-2 only shows poor catalytic activity for reduction and click reaction, and no catalytic activity for homocoupling.

52 citations

Journal ArticleDOI
TL;DR: An efficient and novel 2,5-bis(benzo[d]thiazol-2-yl)phenol scaffold-based ratiometric fluorescent probe BTP-Cys for the sensing of cysteine has been developed and has been successfully constructed on account of the excited state intramolecular proton transfer (ESIPT) mechanism.

41 citations


Cited by
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Journal ArticleDOI
TL;DR: The present review is devoted to summarizing the recent advances (2015–2017) in the field of metal-catalysed group-directed C–H functionalisation.
Abstract: The present review is devoted to summarizing the recent advances (2015-2017) in the field of metal-catalysed group-directed C-H functionalisation In order to clearly showcase the molecular diversity that can now be accessed by means of directed C-H functionalisation, the whole is organized following the directing groups installed on a substrate Its aim is to be a comprehensive reference work, where a specific directing group can be easily found, together with the transformations which have been carried out with it Hence, the primary format of this review is schemes accompanied with a concise explanatory text, in which the directing groups are ordered in sections according to their chemical structure The schemes feature typical substrates used, the products obtained as well as the required reaction conditions Importantly, each example is commented on with respect to the most important positive features and drawbacks, on aspects such as selectivity, substrate scope, reaction conditions, directing group removal, and greenness The targeted readership are both experts in the field of C-H functionalisation chemistry (to provide a comprehensive overview of the progress made in the last years) and, even more so, all organic chemists who want to introduce the C-H functionalisation way of thinking for a design of straightforward, efficient and step-economic synthetic routes towards molecules of interest to them Accordingly, this review should be of particular interest also for scientists from industrial R&D sector Hence, the overall goal of this review is to promote the application of C-H functionalisation reactions outside the research groups dedicated to method development and establishing it as a valuable reaction archetype in contemporary R&D, comparable to the role cross-coupling reactions play to date

1,057 citations

Journal ArticleDOI
TL;DR: A pair of first-generation chemiluminescent probes for selective formaldehyde detection and CFAP700 is capable of visualizing FA release derived from endogenous folate metabolism, providing a starting point for the use of CFAPs and related chemical tools to probe FA physiology and pathology.
Abstract: Formaldehyde (FA) is a common environmental toxin that is also produced naturally in the body through a wide range of metabolic and epigenetic processes, motivating the development of new technologies to monitor this reactive carbonyl species (RCS) in living systems. Herein, we report a pair of first-generation chemiluminescent probes for selective formaldehyde detection. Caging phenoxy-dioxetane scaffolds bearing different electron-withdrawing groups with a general 2-aza-Cope reactive formaldehyde trigger provides chemiluminescent formaldehyde probes 540 and 700 (CFAP540 and CFAP700) for visible and near-IR detection of FA in living cells and mice, respectively. In particular, CFAP700 is capable of visualizing FA release derived from endogenous folate metabolism, providing a starting point for the use of CFAPs and related chemical tools to probe FA physiology and pathology, as well as for the development of a broader palette of chemiluminescent activity-based sensing (ABS) probes that can be employed from in vitro biochemical to cell to animal models.

139 citations

Journal ArticleDOI
TL;DR: In this paper, the most significant developments in fluorescent probes for the detection of the carbonyl species formaldehyde, carbon monoxide and phosgene in recent years, with a special emphasis on their mechanisms and applications.

133 citations

Journal ArticleDOI
TL;DR: A review of reaction-based fluorescent probes for SO2 derivatives can be found in this paper, where the design principles and chemical structures of the probes and their biological applications are highlighted.

113 citations

Journal ArticleDOI
TL;DR: In this paper, a ratiometric fluorescent probe (HBT-FA) based on aza-Cope reaction was designed and synthesized, which showed high selectivity and ratiometric fluorescence response to FA.
Abstract: Developing simple and selective methods for formaldehyde (FA) detection are of great interest, because FA is not only an environmental pollutant, but also an endogenous bioactive molecule. Herein, a new ratiometric fluorescent probe (HBT-FA) based on aza-Cope reaction was designed and synthesized, which showed high selectivity and ratiometric fluorescence response to FA. Furthermore, the probe could detect FA in various medium, such as aqueous solution, serum and air.

98 citations