Showing papers by "Kailash C. Malhotra published in 1993"

Structure of Human Populations in India

Abstract: The interpretation of the temporal and spatial variation of gene frequencies in populations is one of the main aims of population genetics. In addition to systematic evolutionary processes (mutation, selection and admixture), non-systematic factors such as size, density, and the distribution of a population, the nature of mate selection within a population, and differential fertility and viability also influence the genetic composition of a population. These non-systematic factors are the most important components of the structure of human populations. It is now well known that very different patterns of these non-systematic factors exist in human populations.

Study of enzyme polymorphism and haemoglobin patterns amongst sixteen tribal populations of central India (Orissa, Madhya Pradesh, and Maharashtra)

Abstract: A survey was conducted to study the genetic differentiation among 16 tribal groups of Orissa, Madhya Pradesh, and Maharashtra belonging to different ethnic and linguistic affiliations. Sixteen hundred and fifteen blood samples from both sexes were tested for 5 red cell enzyme systems: ACP, ESD, PGD, GLO, LDH, and Hb pattern. Three hundred and nineteen male individuals were tested for G-6-PD enzyme deficiency. The distribution of the enzyme markers and Hb show a range of variation which are more or less within the Indian range. Case of homozygous HbSS were detected in all the tribes except 3 tribes in Orissa. Two cases of LDH Cal-1 homozygote were found in two Dravidian language speaking Orissa tribes. The X2-values for testing the homogeneity of gene frequencies indicate a non-significant heterogeneity for all alleles in the individual system. Within population diversity seems to be larger than between population diversity. The degree of over all genetic differentiation as measured by GST value is 0.0154±0.0071.