K
Kailiang Zhao
Researcher at Wuhan University
Publications - 38
Citations - 355
Kailiang Zhao is an academic researcher from Wuhan University. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 9, co-authored 23 publications receiving 248 citations.
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Clinical characteristics of 101 non-surviving hospitalized patients with COVID-19: A single center, retrospective study
Qiao Shi,Kailiang Zhao,Jia Yu,Fang Jiang,Jiarui Feng,Kaiping Zhao,Xiaoyi Zhang,Xiaoyan Chen,Peng Hu,Yupu Hong,Man Li,Fang Liu,Chen Chen,Weixing Wang +13 more
TL;DR: Older patients (>70 years) with comorbidities had a steeply increased risk of death with COVID-19 and Elevated high sensitivity troponin, neutrophils and depressed oxygen saturation predicted the rapid death of patients.
Journal ArticleDOI
High-Fat Diet Aggravates Acute Pancreatitis via TLR4-Mediated Necroptosis and Inflammation in Rats
Yupu Hong,Jia Yu,Ying-ru Su,Fangchao Mei,Man Li,Kailiang Zhao,Liang Zhao,Wenhong Deng,Chen Chen,Weixing Wang +9 more
TL;DR: Inhibition of TLR4 signaling by TAK-242 alleviated oxidative stress and decreased inflammatory reaction and necroptosis, exerting a protective effect during AP in HFD rats, suggest that HFD exacerbated the extent and severity of AP.
Journal ArticleDOI
Hydrogen-Rich Saline Attenuates Acute Renal Injury in Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting ROS and NF-κB Pathway
Qiao Shi,Kang-Shu Liao,Kailiang Zhao,Weixing Wang,Teng Zuo,Wenhong Deng,Chen Chen,Jia Yu,Wenyi Guo,Xiaobo He,Ablikim Abliz,Peng Wang,Liang Zhao +12 more
TL;DR: Results proved that hydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced acute pancreatitis, presumably because of its detoxification activity against excessive ROS, and inhibits the activation of NF-κB by affecting IκB nitration and degradation.
Journal ArticleDOI
Apocynin alleviates lung injury by suppressing NLRP3 inflammasome activation and NF-κB signaling in acute pancreatitis.
TL;DR: It is observed that apocynin significantly attenuated severe acute pancreatitis-induced increase of NOX2, NOX4 and ROS expressions in lung tissues and may have therapeutic potential in the treatment of SAP and SAP-induced lung injury.
Journal ArticleDOI
Hydrogen-Rich Saline Attenuates Acute Hepatic Injury in Acute Necrotizing Pancreatitis by Inhibiting Inflammation and Apoptosis, Involving JNK and p38 Mitogen-Activated Protein Kinase-dependent Reactive Oxygen Species.
Qiao Shi,Chen Chen,Wenhong Deng,Peng Wang,Teng Zuo,Liang Zhao,Jia Yu,Kailiang Zhao,Fangchao Mei,Chen Li,Guirong Wang,Weixing Wang +11 more
TL;DR: Hydrogen-rich saline plays a protective role in ANP-induced AHI through inhibiting inflammation and apoptosis, involving JNK and p38 MAPK-dependent reactive oxygen species.