Showing papers by "Kalpattu K. Balasubramanian published in 2007"
TL;DR: Highly deactivated aromatic compounds were smoothly monobrominated by treatment with N-bromosuccinimide (NBS) in concentrated H2SO4 medium affording the corresponding bromo derivatives in good yields.
Abstract: Highly deactivated aromatic compounds were smoothly monobrominated by treatment with N-bromosuccinimide (NBS) in concentrated H2SO4 medium affording the corresponding bromo derivatives in good yields. Mild reaction conditions and simple workup provides a practical and commercially viable route for the synthesis of bromo compounds of deactivated aromatics.
79 citations
TL;DR: A series of substituted 1-(2-arylmethyl-5-aryl-3-thienyl)pyrrolidines and piperidines were synthesized by one-pot, three-component tandem reactions of 5-aryldihydro-3(2 H )-thiophenone, aromatic aldehydes and pyrrolidine/piperidine under solvent-free microwave irradiation as discussed by the authors.
12 citations
TL;DR: In this article, high deactivated aromatic compounds were smoothly monobrominated by treatment with N-bromosuccinimide (NBS) in concentrated H2SO4 medium affording the corresponding bromo derivatives in good yields.
Abstract: Highly deactivated aromatic compounds were smoothly monobrominated by treatment with N-bromosuccinimide (NBS) in concentrated H2SO4 medium affording the corresponding bromo derivatives in good yields. Mild reaction conditions and simple workup provides a practical and commercially viable route for the synthesis of bromo compounds of deactivated aromatics.
7 citations
TL;DR: A series of substituted 1-(2-arylmethyl-5-aryl-3-thienyl)pyrrolidines and piperidines were synthesized by one-pot, three-component tandem reactions of 5-aryldihydro-3(2 H )-thiophenone, aromatic aldehydes and pyrrolidine/piperidine under solvent-free microwave irradiation as mentioned in this paper.
Abstract: A series of new substituted 1-(2-arylmethyl-5-aryl-3-thienyl)pyrrolidines and piperidines were synthesised by one-pot, three-component tandem reactions of 5-aryldihydro-3(2 H )-thiophenone, aromatic aldehydes and pyrrolidine/piperidine under solvent-free microwave irradiation. This facile transformation occurs presumably via a tandem enamine formation–carbonyl addition–dehydration–isomerisation sequence.