K
Kanar Alkass
Researcher at Karolinska Institutet
Publications - 46
Citations - 8588
Kanar Alkass is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Neurogenesis & Medicine. The author has an hindex of 22, co-authored 41 publications receiving 7282 citations.
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Journal ArticleDOI
Evidence for cardiomyocyte renewal in humans
Olaf Bergmann,Ratan D. Bhardwaj,Samuel Bernard,Sofia Zdunek,Fanie Barnabé-Heider,Stuart Walsh,Joel Zupicich,Kanar Alkass,Bruce A. Buchholz,Henrik Druid,Stefan Jovinge,Jonas Frisén +11 more
TL;DR: The capacity to generate cardiomyocytes in the adult human heart suggests that it may be rational to work toward the development of therapeutic strategies aimed at stimulating this process in cardiac pathologies.
Journal ArticleDOI
Dynamics of Hippocampal Neurogenesis in Adult Humans
Kirsty L. Spalding,Olaf Bergmann,Kanar Alkass,Samuel Bernard,Mehran Salehpour,Hagen B. Huttner,Hagen B. Huttner,Emil Boström,Isabelle Westerlund,Céline Vial,Bruce A. Buchholz,Göran Possnert,Deborah C. Mash,Henrik Druid,Jonas Frisén +14 more
TL;DR: It is concluded that neurons are generated throughout adulthood and that the rates are comparable in middle-aged humans and mice, suggesting that adult hippocampal neurogenesis may contribute to human brain function.
Journal ArticleDOI
Dynamics of Cell Generation and Turnover in the Human Heart
Olaf Bergmann,Sofia Zdunek,Anastasia Felker,Mehran Salehpour,Kanar Alkass,Samuel Bernard,Staffan L. Sjostrom,Mirosława Szewczykowska,Teresa Jackowska,Cris dos Remedios,Torsten Malm,Michaela Andrä,Ramadan Jashari,Jens R. Nyengaard,Göran Possnert,Stefan Jovinge,Stefan Jovinge,Stefan Jovinge,Henrik Druid,Jonas Frisén +19 more
TL;DR: It is reported that the full complement of cardiomyocytes is established perinataly and remains stable over the human lifespan, whereas the numbers of both endothelial and mesenchymal cells increase substantially from birth to early adulthood.
Journal ArticleDOI
Neurogenesis in the Striatum of the Adult Human Brain
Aurélie Ernst,Kanar Alkass,Samuel Bernard,Mehran Salehpour,Shira Perl,John F. Tisdale,Göran Possnert,Henrik Druid,Jonas Frisén +8 more
TL;DR: It is shown that in adult humans new neurons integrate in the striatum, which is adjacent to this neurogenic niche, and this findings demonstrate a unique pattern of neurogenesis in the adult human brain.
Journal ArticleDOI
Dynamics of oligodendrocyte generation and myelination in the human brain.
Maggie S. Y. Yeung,Sofia Zdunek,Olaf Bergmann,Samuel Bernard,Mehran Salehpour,Kanar Alkass,Shira Perl,John F. Tisdale,Göran Possnert,Lou Brundin,Henrik Druid,Jonas Frisén +11 more
TL;DR: It is concluded that oligodendrocyte turnover contributes minimally to myelin modulation in human white matter and that this instead may be carried out by mature oligodendedrocytes, which may facilitate rapid neural plasticity.