K
Karen A. McCaustland
Researcher at Centers for Disease Control and Prevention
Publications - 34
Citations - 5937
Karen A. McCaustland is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Virus & Hepatitis E virus. The author has an hindex of 25, co-authored 34 publications receiving 5549 citations. Previous affiliations of Karen A. McCaustland include Chiron Corporation & Government of the United States of America.
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Journal ArticleDOI
Characterization of a novel coronavirus associated with severe acute respiratory syndrome.
Paul A. Rota,M. Steven Oberste,Stephan S. Monroe,W. Allan Nix,Ray Campagnoli,Joseph P. Icenogle,Silvia Peñaranda,Bettina Bankamp,Kaija Maher,Min hsin Chen,Suxiong Tong,Azaibi Tamin,Luis Lowe,Michael Frace,Joseph L. DeRisi,Qi Chen,David Wang,Dean D. Erdman,Teresa C. T. Peret,Cara C. Burns,Thomas G. Ksiazek,Pierre E. Rollin,Anthony Sanchez,Stephanie L. Liffick,Brian P. Holloway,Josef Limor,Karen A. McCaustland,Mellissa Olsen-Rasmussen,Ron A. M. Fouchier,Stephan Günther,Albert Osterhaus,Christian Drosten,Mark A. Pallansch,Larry J. Anderson,William J. Bellini +34 more
TL;DR: Phylogenetic analyses and sequence comparisons showed that SARS-CoV is not closelyrelated to any of the previouslycharacterized coronaviruses.
Journal ArticleDOI
Evaluation and Improvement of Real-Time PCR Assays Targeting lytA, ply, and psaA Genes for Detection of Pneumococcal DNA
Maria da Gloria Carvalho,Maria Lucia Tondella,Karen A. McCaustland,Luciana Weidlich,Lesley McGee,Leonard W. Mayer,Arnold G. Steigerwalt,Melissa J. Whaley,Richard R. Facklam,Barry S. Fields,George M. Carlone,Edwin W. Ades,Ron Dagan,Jacquelyn S. Sampson +13 more
TL;DR: Three novel real-time PCR assays designed for the detection of specific sequence regions of the lytA, ply, and psaA genes were developed and should be considered the assays of choice for the Detection of pneumococcal DNA, particularly when upper respiratory P-LVS might be present in the clinical specimen.
Journal ArticleDOI
Detection of pathogenic Leptospira spp. through TaqMan polymerase chain reaction targeting the LipL32 gene
TL;DR: A real-time PCR assay using a TaqMan probe targeting lipL32, which is present only in pathogenic Leptospira spp, with high specificity and sensitivity may prove to be a rapid method for diagnosing acute leptospirosis.
Journal ArticleDOI
Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus.
Shannon L. Emery,Dean D. Erdman,Michael D. Bowen,Bruce R. Newton,Jonas M. Winchell,Richard F. Meyer,Suxiang Tong,Byron T. Cook,Brian P. Holloway,Karen A. McCaustland,Paul A. Rota,Bettina Bankamp,Luis Lowe,Thomas G. Ksiazek,William J. Bellini,Larry J. Anderson +15 more
TL;DR: A real-time reverse transcription–polymerase chain reaction (RT-PCR) assay was developed to rapidly detect the severe acute respiratory syndrome–associated coronavirus (SARS-CoV) and proved suitable to detect SARS- coV in clinical specimens.
Journal ArticleDOI
Use of TaqMan Real-Time Reverse Transcription-PCR for Rapid Detection, Quantification, and Typing of Norovirus
A. Angelica Trujillo,Karen A. McCaustland,Du Ping Zheng,Leslie A. Hadley,George Vaughn,Susan M. Adams,Tamie Ando,Roger I. Glass,Stephan S. Monroe +8 more
TL;DR: The TaqMan methods dramatically decrease the turnaround time by eliminating post-PCR processing and have proven useful in assisting scientists in public health and diagnostic laboratories report findings quickly to outbreak management teams.