K
Karen Clements
Researcher at Public Health England
Publications - 53
Citations - 604
Karen Clements is an academic researcher from Public Health England. The author has contributed to research in topics: Breast cancer & Medicine. The author has an hindex of 12, co-authored 32 publications receiving 438 citations. Previous affiliations of Karen Clements include University of Birmingham.
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Journal ArticleDOI
Cost-effectiveness Analysis of Universal Influenza Vaccination With Quadrivalent Inactivated Vaccine in the United States
TL;DR: Vaccination with IIV4 in the US is predicted to reduce morbidity and mortality and is also predicted to be cost-effective vs. IIV3/LAIV3 at conventional willingness-to-pay thresholds.
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The effect of DCIS grade on rate, type and time to recurrence after 15 years of follow-up of screen-detected DCIS.
TL;DR: Long-term follow-up of patients diagnosed with DCIS diagnosed in the first 10 years of the West Midlands NHSBSP will miss significant numbers of events, especially invasive local recurrences.
Journal ArticleDOI
Risk factors for the development of invasive cancer in unresected ductal carcinoma in situ.
Anthony J. Maxwell,Karen Clements,Bridget Hilton,David Dodwell,Andrew Evans,Olive Kearins,Sarah E Pinder,Jeremy Thomas,Matthew G. Wallis,Alastair M. Thompson +9 more
TL;DR: High cytonuclear grade, mammographic microcalcification, young age and lack of endocrine therapy were risk factors for DCIS progression to invasive cancer.
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Radiological and pathological size estimations of pure ductal carcinoma in situ of the breast, specimen handling and the influence on the success of breast conservation surgery: a review of 2564 cases from the Sloane Project
Jeremy Thomas,Andrew Evans,J Macartney,Sarah E Pinder,A. Hanby,Ian O. Ellis,Olive Kearins,Tracy E Roberts,Karen Clements,Gill Lawrence,H Bishop +10 more
TL;DR: In 30% of patients undergoing BCS for DCIS, preoperative imaging underestimates the extent of disease resulting in a requirement for further surgery, suggesting specimen-handling techniques as a cause for second operations to be reduced to a minimum.
Journal ArticleDOI
Management and 5-year outcomes in 9938 women with screen-detected ductal carcinoma in situ: the UK Sloane Project
Alastair M. Thompson,Karen Clements,S. Cheung,Sarah E Pinder,G Lawrence,Elinor J. Sawyer,Olive Kearins,Graham Ball,Ian Tomlinson,Andrew M. Hanby,Thomas Jsj.,Anthony J. Maxwell,Matthew G. Wallis,David Dodwell +13 more
TL;DR: Recurrent DCIS or invasive cancer is uncommon after screen-detected DCIS and both RT and endocrine therapy were associated with a reduction in further events but not with breast cancer mortality within 5 years of diagnosis.