K
Karen L Craig
Researcher at Mount Sinai Hospital
Publications - 2
Citations - 1095
Karen L Craig is an academic researcher from Mount Sinai Hospital. The author has contributed to research in topics: Cyclin-dependent kinase & Sic1. The author has an hindex of 2, co-authored 2 publications receiving 1069 citations.
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Journal ArticleDOI
The Phosphatase Cdc14 Triggers Mitotic Exit by Reversal of Cdk-Dependent Phosphorylation
TL;DR: This work shows that the Cdc14 phosphatase triggers mitotic exit by three parallel mechanisms, each of which inhibits Cdk activity, and induces degradation of mitotic cyclins.
Journal ArticleDOI
Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway.
Andrew Willems,Stefan Lanker,E.Elizabeth Patton,E.Elizabeth Patton,Karen L Craig,Timothy F Nason,Neal Mathias,Ryuji Kobayashi,Curt Wittenberg,Mike Tyers,Mike Tyers +10 more
TL;DR: Findings suggest that Cdc53 is a component of a ubiquitin-protein ligase complex that targets phosphorylated G1 cyclins for degradation by the ubiquit in-proteasome pathway.