K
Karen Sugden
Researcher at Duke University
Publications - 91
Citations - 17079
Karen Sugden is an academic researcher from Duke University. The author has contributed to research in topics: Population & DNA methylation. The author has an hindex of 34, co-authored 82 publications receiving 14617 citations. Previous affiliations of Karen Sugden include University of London & University of Wisconsin-Madison.
Papers
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Journal ArticleDOI
Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene
Avshalom Caspi,Karen Sugden,Terrie E. Moffitt,Alan Taylor,Ian W. Craig,Hona Lee Harrington,Joseph L. McClay,Jonathan Mill,Judy Martin,Antony W. Braithwaite,Richie Poulton +10 more
TL;DR: Evidence of a gene-by-environment interaction is provided, in which an individual's response to environmental insults is moderated by his or her genetic makeup.
Journal ArticleDOI
Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene
Avshalom Caspi,Karen Sugden,Terrie E. Moffitt,Alan Taylor,Ian W. Craig,Hona Lee Harrington,Joseph L. McClay,Jonathan Mill,Judy Martin,Antony W. Braithwaite,Richie Poulton +10 more
TL;DR: Evidence of a gene-by-environment interaction is provided, in which an individual's response to environmental insults is moderated by his or her genetic makeup.
Journal ArticleDOI
Gene-environment interaction analysis of serotonin system markers with adolescent depression.
Thalia C. Eley,Karen Sugden,A Corsico,Alice M. Gregory,Pak C. Sham,Peter McGuffin,Robert Plomin,Ian W. Craig +7 more
TL;DR: In this paper, the authors report analyses from a study of gene-environment interaction in adolescent depression using DNA from 377 adolescents, representing the four quadrants of high or low depression.
Journal ArticleDOI
Quantification of biological aging in young adults.
Daniel W. Belsky,Avshalom Caspi,Renate Houts,Harvey J. Cohen,David L. Corcoran,Andrea Danese,HonaLee Harrington,Salomon Israel,Morgan E. Levine,Jonathan D. Schaefer,Karen Sugden,Ben Williams,Anatoli I. Yashin,Richie Poulton,Terrie E. Moffitt +14 more
TL;DR: It is indicated that aging processes can be quantified in people still young enough for prevention of age-related disease, opening a new door for antiaging therapies.
Journal ArticleDOI
Is Adult ADHD a Childhood-Onset Neurodevelopmental Disorder? Evidence From a Four-Decade Longitudinal Cohort Study
Terrie E. Moffitt,Renate Houts,Philip Asherson,Daniel W. Belsky,David L. Corcoran,Maggie Hammerle,HonaLee Harrington,Sean Hogan,Madeline H. Meier,Guilherme V. Polanczyk,Richie Poulton,Sandhya Ramrakha,Karen Sugden,Benjamin Williams,Luis Augusto Rohde,Avshalom Caspi +15 more
TL;DR: The findings raise the possibility that adults presenting with the ADHD symptom picture may not have a childhood-onset neurodevelopmental disorder, and the disorder's place in the classification system must be reconsidered.