K
Kari Alitalo
Researcher at University of Helsinki
Publications - 844
Citations - 122462
Kari Alitalo is an academic researcher from University of Helsinki. The author has contributed to research in topics: Angiogenesis & Vascular endothelial growth factor C. The author has an hindex of 174, co-authored 817 publications receiving 114231 citations. Previous affiliations of Kari Alitalo include Mount Sinai Hospital, Toronto & Cornell University.
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Patent
Use of VEGF-C to prevent restenosis
TL;DR: In this paper, the authors present materials and methods for preventing stenosis or restenosis of a blood vessel using Vascular Endothelial Growth Factor C (VEGF-C) and/or vascular endothelial growth Factor D (VEGF-D) genes or proteins.
Journal ArticleDOI
Retrograde Lymph Flow Leads to Chylothorax in Transgenic Mice with Lymphatic Malformations
Maximilian Nitschké,Alexander Bell,Sinem Karaman,Meelad Amouzgar,Joseph M. Rutkowski,Philipp E. Scherer,Kari Alitalo,Donald M. McDonald +7 more
TL;DR: Findings indicate that chylothorax in ADN-VEGF-C mice results from retrograde flow of chyle from the thoracic duct into lymphatic tributaries with defective valves.
Journal ArticleDOI
Co-amplification of a novel cyclophilin-like gene (PPIE) with L-myc in small cell lung cancer cell lines.
Ju-Ock Kim,Marion M. Nau,Kathrine A Allikian,Tomi P. Mäkelä,Kari Alitalo,Bruce E. Johnson,Michael J. Kelley +6 more
TL;DR: This gene, tentatively named PPIE (peptidyl-prolyl cis-trans isomerase E), has 83% amino acid identity with the central conserved region of cyclophilin A, is evolutionarily conserved by Southern blot, and exhibits differential tissue expression with highest levels found in muscle and brain.
Journal ArticleDOI
Deposition of an intermediate form of procollagen type III (pN-collagen) into fibrils in the matrix of amniotic epithelial cells.
TL;DR: It is concluded that the deposition of this intermediate form of procollagen is a general mechanism in collagen type III fibrillogenesis.
Patent
Growth factor binding constructs materials and methods
Kari Alitalo,Markku M. Jeltsch +1 more
TL;DR: In this article, materials and methods for antagonizing the function of vascular endothelial growth factor receptors, platelet derived growth factor receptor and other receptors are presented. But none of these methods can be used to antagonize the functions of other receptors.