Kari Alitalo

TL;DR: A VEGFR-2-specific form of VEGF-D that is angiogenic but not lymphangiogenic is defined, providing important new insights into VEGf-D structure and function.

TL;DR: Rak is a novel epithelial-associated nuclear tyrosine kinase that may represent a unique subfamily of the Src-related kinases.

TL;DR: The results suggest that in large arteries VEGF-D is mainly expressed in smooth muscle cells and that it may have a role in the maintenance of vascular homeostasis and in complicated lesions it was also expressed in macrophages and may contribute to plaque neovascularization.

TL;DR: The results help to define possibilities for local angiogenic therapy around blood vessels and support the concept thatAngiogenic effects may be tissue-specific and depend both on the growth factor ligands and the target tissues.

TL;DR: Results of bone marrow transplantation studies showed that Bmx in bone marrow-derived cells plays a critical role in the early phase of ischemic tissue remodeling, the first demonstration to the knowledge that BMX in endothelium and bone marrow plays acritical role in arteriogenesis/angiogenesis in vivo and suggests that B MX may be a novel target for the treatment of vascular diseases such as coronary artery disease and peripheral arterial disease.