K
Karina B. Xavier
Researcher at Instituto Gulbenkian de Ciência
Publications - 71
Citations - 6068
Karina B. Xavier is an academic researcher from Instituto Gulbenkian de Ciência. The author has contributed to research in topics: Quorum sensing & Autoinducer-2. The author has an hindex of 31, co-authored 62 publications receiving 5223 citations. Previous affiliations of Karina B. Xavier include Howard Hughes Medical Institute & Princeton University.
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Journal ArticleDOI
LuxS quorum sensing: more than just a numbers game.
TL;DR: Most autoinducers enable intraspecies communication; however, a recently discovered autoinducer AI-2 has been proposed to serve as a 'universal signal' for interspecies communication.
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The Multiple Signaling Systems Regulating Virulence in Pseudomonas aeruginosa
Pol Nadal Jimenez,Pol Nadal Jimenez,Gudrun Koch,Gudrun Koch,Jessica A. Thompson,Karina B. Xavier,Robbert H. Cool,Wim J. Quax +7 more
TL;DR: This overview clearly illustrates that bacterial communication is far more complex than initially thought and delivers a clear distinction between signals that are quorum sensing dependent and those relying on alternative factors for their production.
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Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2
Stephen T. Miller,Karina B. Xavier,Shawn R. Campagna,Michiko E. Taga,Martin F. Semmelhack,Bonnie L. Bassler,Frederick M. Hughson +6 more
TL;DR: It is demonstrated that two different species of bacteria recognize two different forms of the autoinducer signal, both derived from 4,5-dihydroxy-2,3-pentanedione (DPD), and new sophistication in the chemical lexicon used by bacteria in interspecies signaling is revealed.
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AI‐2‐mediated signalling in bacteria
Catarina S. Pereira,Catarina S. Pereira,Jessica A. Thompson,Jessica A. Thompson,Karina B. Xavier,Karina B. Xavier +5 more
TL;DR: A comprehensive review of the discovery and early characterization of AI-2, current developments in signal detection, transduction and regulation, and the major studies investigating the phenotypes regulated by this molecule is presented.
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Regulation of Uptake and Processing of the Quorum-Sensing Autoinducer AI-2 in Escherichia coli
TL;DR: It is shown that, depending on the prevailing growth conditions, the amount of time that the AI-2 signal is present and, in turn, the time that a given community of bacteria remains exposed to this signal can vary greatly.