K
Karina Vargas-Sánchez
Researcher at University of Los Andes
Publications - 7
Citations - 441
Karina Vargas-Sánchez is an academic researcher from University of Los Andes. The author has contributed to research in topics: Neuroinflammation & Inflammation. The author has an hindex of 4, co-authored 5 publications receiving 264 citations.
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Journal ArticleDOI
Involvement of Astrocytes in Alzheimer's Disease from a Neuroinflammatory and Oxidative Stress Perspective.
Rodrigo E. González-Reyes,Mauricio O. Nava-Mesa,Karina Vargas-Sánchez,Daniel Ariza-Salamanca,Laura Mora-Muñoz +4 more
TL;DR: The Aβ/NF-κB interaction in astrocytes may play a central role in these inflammatory and OS changes present in AD, and therapeutic measures highlighting the importance of astroCytes in AD pathology are discussed.
Journal ArticleDOI
Astroglial role in the pathophysiology of status epilepticus: an overview.
Karina Vargas-Sánchez,Maria Mogilevskaya,John Rodríguez-Pérez,María Graciela Rubiano,José J Javela,Rodrigo E. González-Reyes +5 more
TL;DR: This review focuses on the functional and structural changes in astrocytic activity that participate in the development and maintenance of status epilepticus, with special attention on concurrent inflammatory alterations.
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Effects of Moringa oleifera on Glycaemia and Insulin Levels: A Review of Animal and Human Studies.
TL;DR: The evidence for acute antihyperglycemic effects of MO extract on diabetic animal models seems to be robust, but more chronic and long-term studies are needed to clarify if MO has an effect on insulin levels or activity.
Journal ArticleDOI
PPARα and PPARβ/δ are negatively correlated with proinflammatory markers in leukocytes of an obese pediatric population
Karina Vargas-Sánchez,Laura Vargas,Yenny Urrutia,Iván Beltrán,Ana Beatriz Rossi,Hernán Yupanqui Lozano,Jorge Guarín,Monica Losada-Barragán +7 more
TL;DR: PPARα and PPARβ/δ expression are negatively correlated with the proinflammatory markers TNF-α and IL-8, respectively, suggesting participation in the regulation of inflammation which was observed to be altered in pediatric obesity.
Journal ArticleDOI
Laminin as a Biomarker of Blood–Brain Barrier Disruption under Neuroinflammation: A Systematic Review
Juan F. Zapata-Acevedo,Valentina García-Pérez,Ricardo Cabezas-Perez,Monica Losada-Barragán,Karina Vargas-Sánchez,Rodrigo E. González-Reyes +5 more
TL;DR: It is found that laminin may be a good indicator of BBB overall structural integrity, although changes in expression are dependent on the pathologic or experimental model used.