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Author

Karl Fent

Bio: Karl Fent is an academic researcher from University of Applied Sciences and Arts Northwestern Switzerland FHNW. The author has contributed to research in topics: Zebrafish & Vitellogenin. The author has an hindex of 49, co-authored 135 publications receiving 9564 citations. Previous affiliations of Karl Fent include ETH Zurich & École Polytechnique Fédérale de Lausanne.


Papers
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TL;DR: It is shown that only very little is known about long-term effects of pharmaceuticals to aquatic organisms, in particular with respect to biological targets, and targeted ecotoxicological studies are needed focusing on subtle environmental effects.

2,844 citations

Journal ArticleDOI
TL;DR: Nine hormonally active UV-filters by LC-MS/MS and GC-MS in river water and biota and 48 macroinvertebrate and fish samples from six rivers lipid-weighted EHMC occurred, suggesting food-chain accumulation, are found to be ubiquitous in aquatic systems.

366 citations

Journal ArticleDOI
TL;DR: It is concluded that receptor-based assays are important for in vitro assessment of UV-filters prior to or concurrently with in vivo assays, which ultimately provide data for the environmental risk assessment of these important personal care products.

266 citations

Journal ArticleDOI
TL;DR: The study shows, for the first time, estrogenic activities of UV filters in fish both in vitro and in vivo, and proposes that receptor-based assays should be used for in vitro screening prior to in vivo testing, leading to environmental risk assessments based on combined, complementary, and appropriate species-related assays for hormonal activity.

248 citations

Journal ArticleDOI
TL;DR: The mode of action concept is found to be most suitable for the identification of highly active compounds (HC), and a refinement can be achieved by complementing this concept by the QSAR model (VirtualTox Lab), whereas the fish plasma model seemed to be less suitable due to the necessity of environmental concentration above 10ng/L for the Identification of a risk.

209 citations


Cited by
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Journal ArticleDOI
TL;DR: There is little doubt that measurements of bioaccumulation and biomarker responses in fish from contaminated sites offer great promises for providing information that can contribute to environmental monitoring programs designed for various aspects of ERA.

4,397 citations

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TL;DR: This review brings up important questions that are still open, and addresses some significant issues which must be tackled in the future for a better understanding of the behavior of antibiotics in the environment, as well as the risks associated with their occurrence.

3,620 citations

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TL;DR: This review provides a summary of the recent occurrence of micropollutants in the aquatic environment including sewage, surface water, groundwater and drinking water.

2,933 citations

Journal ArticleDOI
TL;DR: It is shown that microplastic contaminates the shorelines at 18 sites worldwide representing six continents from the poles to the equator, with more material in densely populated areas, but no clear relationship between the abundance of miocroplastics and the mean size-distribution of natural particulates.
Abstract: Plastic debris 1900 fibers per wash. This suggests that a large proportion of microplastic fibers found in the marine environment may be derived from sewage as a consequence of washing of clothes. As the human population grows and people use more synthetic textiles, contamination of habitats and animals by microplastic is likely to increase.

2,903 citations

Journal ArticleDOI
TL;DR: This paper has attempted to summarize the latest information available in the literature on the use, sales, exposure pathways, environmental occurrence, fate and effects of veterinary antibiotics in animal agriculture.

2,856 citations