K
Karl Schellander
Researcher at University of Bonn
Publications - 357
Citations - 10310
Karl Schellander is an academic researcher from University of Bonn. The author has contributed to research in topics: Gene & Population. The author has an hindex of 49, co-authored 352 publications receiving 9324 citations. Previous affiliations of Karl Schellander include Laval University & Research Institute of Molecular Pathology.
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Journal ArticleDOI
Imprinted expression of the Igf2r gene depends on an intronic CpG island
Anton Wutz,Oskar W. Smrzka,Norbert Schweifer,Karl Schellander,Erwin F. Wagner,Denise P. Barlow +5 more
TL;DR: A primary role for region 2 is defined and a negligible role for chromosomal location is defined in Igf2r imprinting; they show that methylation imprints can maintain allelic expression and that expression competition could play a general role in imprinting.
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Osteoblasts are target cells for transformation in c-fos transgenic mice.
TL;DR: It is suggested that high levels of Fos perturb the normal growth control of osteoblastic cells and exert specific effects on the expression of the osteoblast phenotype.
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Large-scale transcriptional analysis of bovine embryo biopsies in relation to pregnancy success after transfer to recipients.
Ashraf M. El-Sayed,Michael Hoelker,Franca Rings,Dessie Salilew,Danyel Jennen,Ernst Tholen,Marc-André Sirard,Karl Schellander,Dawit Tesfaye +8 more
TL;DR: Direct candidates of blastocyst-specific genes which may play an important role in determining the fate of the embryo after transfer are generated.
Journal ArticleDOI
Exosomal and Non-Exosomal Transport of Extra-Cellular microRNAs in Follicular Fluid: Implications for Bovine Oocyte Developmental Competence.
Md. Mahmodul Hasan Sohel,Michael Hoelker,Sina Seifi Noferesti,Dessie Salilew-Wondim,Ernst Tholen,Christian Looft,Franca Rings,Muhammad Jasim Uddin,Thomas E. Spencer,Karl Schellander,Dawit Tesfaye +10 more
TL;DR: The presence of exosome or non-exosome mediated transfer of miRNA in the bovine follicular fluid, and oocyte growth dependent variation in extra-cellular miRNA signatures in the follicular environment is demonstrated for the first time.
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The Human Ubiquitin C Promoter Directs High Ubiquitous Expression of Transgenes in Mice
Marina Schorpp,Richard Jäger,Karl Schellander,Johannes Schenkel,Erwin F. Wagner,Hans Weiher,Peter Angel +6 more
TL;DR: The application of a powerful expression vector using the 5′-flanking region of the human ubiquitin C gene that allows very efficient expression of a given transgene in a broad range of tissues is reported.