K
Karla M. Neugebauer
Researcher at Yale University
Publications - 121
Citations - 10153
Karla M. Neugebauer is an academic researcher from Yale University. The author has contributed to research in topics: RNA splicing & Intron. The author has an hindex of 50, co-authored 112 publications receiving 8976 citations. Previous affiliations of Karla M. Neugebauer include University of California, San Francisco & Baylor College of Medicine.
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Journal ArticleDOI
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
Ralf Kittler,Gabriele Putz,Laurence Pelletier,Ina Poser,Anne-Kristin Heninger,David N. Drechsel,Steffi Fischer,Irena Konstantinova,Bianca Habermann,Hannes Grabner,Marie-Laure Yaspo,Heinz Himmelbauer,Bernd Korn,Karla M. Neugebauer,Maria Teresa Pisabarro,Maria Teresa Pisabarro,Frank Buchholz +16 more
TL;DR: This study uncovers new aspects of cell division and establishes esiRNA as a versatile approach for genomic RNAi screens in mammalian cells.
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Distinct functions of SR proteins in alternative pre-mRNA splicing
TL;DR: It is demonstrated that particular SR proteins have distinct functions in alternative pre-mRNA splicing in vitro, and this results suggest a fundamental role for SR proteins in the regulation of alternative splicing.
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N-Cadherin and Integrins: Two Receptor Systems That Mediate Neuronal Process Outgrowth on Astrocyte Surfaces
Kevin J. Tomaselli,Karla M. Neugebauer,John L. Bixby,Jack Lilien,Louis F. Reichard,Louis F. Reichard +5 more
TL;DR: Since N-cadherin and integrin beta 1 antibodies together virtually eliminated E8 CG neurite outgrowth on cultured astrocytes, these two neuronal receptors are probably important in regulating axon growth on astroglia in vivo.
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How cells get the message: dynamic assembly and function of mRNA–protein complexes
TL;DR: This work has highlighted the importance of mRNP packaging, which can sort RNAs on the basis of their length and determine mRNA fate through alternative mR NP assembly, processing and export pathways.
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N-cadherin, NCAM, and integrins promote retinal neurite outgrowth on astrocytes in vitro.
TL;DR: N-cadherin, integrins, and NCAM are likely to regulate axon extension in the optic pathway, and their relative importance varies with developmental age.