K
Karsten Mäder
Researcher at Martin Luther University of Halle-Wittenberg
Publications - 243
Citations - 16140
Karsten Mäder is an academic researcher from Martin Luther University of Halle-Wittenberg. The author has contributed to research in topics: Drug delivery & Controlled release. The author has an hindex of 53, co-authored 232 publications receiving 14433 citations. Previous affiliations of Karsten Mäder include Hoffmann-La Roche & Translational Centre for Regenerative Medicine.
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Journal ArticleDOI
Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art.
TL;DR: Relevant issues for the introduction of SLN to the pharmaceutical market, such as status of excipients, toxicity/tolerability aspects and sterilization and long-term stability including industrial large scale production are discussed.
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Solid lipid nanoparticles: Production, characterization and applications
W. Mehnert,Karsten Mäder +1 more
TL;DR: An overview about the selection of the ingredients, different ways of SLN production and SLN applications, and the in vivo fate of the carrier are presented.
Journal ArticleDOI
Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy
TL;DR: The investigated SLN appear as thin platelets with oil spots sticking on the surface and very short diffusion pathways in platelets, increased water-lipid interfaces and low drug incorporation in crystalline lipids are the drawback of SLN and NLC compared to conventional nanoemulsions.
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Nanoparticles with decreasing surface hydrophobicities: influence on plasma protein adsorption.
TL;DR: Investigation of changes in the plasma protein adsorption patterns in the course of surface hydrophobicity variation finds correlations with physicochemical characteristics found and are discussed.