K
Karyn E. Medcalf
Researcher at University of Toronto
Publications - 4
Citations - 881
Karyn E. Medcalf is an academic researcher from University of Toronto. The author has contributed to research in topics: Viral load & Cytotoxic T cell. The author has an hindex of 4, co-authored 4 publications receiving 532 citations.
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Journal ArticleDOI
Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies
TL;DR: A practical evidence based list of clinical risk factors that can be assessed by a clinician at ≤16 weeks’ gestation to estimate a woman’s risk of pre-eclampsia and the use of aspirin prophylaxis in pregnancy is developed.
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Clinical Risk Factors for Preeclampsia Determined in Early Pregnancy: Systematic Review and Meta-Analysis of Large Cohort Studies
TL;DR: A meta-analysis of cohort studies examining risk factors for preeclampsia identified multiple risk factors that could be used to identify early in pregnancy women who are at “high risk” of developing preeClampsia.
Journal ArticleDOI
Soluble T Cell Immunoglobulin Mucin Domain 3 Is Shed from CD8+ T Cells by the Sheddase ADAM10, Is Increased in Plasma during Untreated HIV Infection, and Correlates with HIV Disease Progression
Kiera L. Clayton,Matthew Douglas-Vail,A. K. M. Nur-ur Rahman,Karyn E. Medcalf,Irene Y. Xie,Glen M. Chew,Ravi Tandon,Marion C. Lanteri,Philip J. Norris,Philip J. Norris,Steven G. Deeks,Lishomwa C. Ndhlovu,Mario A. Ostrowski +12 more
TL;DR: It is found that shedding Tim-3 did not improve the function of CD8+ T cells in terms of gamma interferon production or prevent their apoptosis through galectin-9, and sTim-3 may represent a new correlate of HIV disease progression.
Journal ArticleDOI
Association of Newborn Apgar Score With Maternal Admission to the Intensive Care Unit
TL;DR: The newborn 5-minute Apgar score is routinely collected and its association with maternal admission to the ICU was assessed.