K
Katarzyna Piwocka
Researcher at Nencki Institute of Experimental Biology
Publications - 98
Citations - 2521
Katarzyna Piwocka is an academic researcher from Nencki Institute of Experimental Biology. The author has contributed to research in topics: Apoptosis & Leukemia. The author has an hindex of 27, co-authored 86 publications receiving 2050 citations. Previous affiliations of Katarzyna Piwocka include University College Cork.
Papers
More filters
Journal ArticleDOI
Induction of senescence with doxorubicin leads to increased genomic instability of HCT116 cells.
Malgorzata A. Sliwinska,Grazyna Mosieniak,Kamila Wolanin,Aneta Babik,Katarzyna Piwocka,Adriana Magalska,Joanna Szczepanowska,Jan Fronk,Ewa Sikora +8 more
TL;DR: A senescence-inducing treatment of HCT116 cancer cells had a dual effect-it stopped the proliferation of the majority of the cells, but also led to the appearance of proliferating aneuploid ones.
Journal ArticleDOI
Curcumin induces apoptosis-independent death in oesophageal cancer cells
G. O’Sullivan-Coyne,Gerald C. O'Sullivan,Tracey R. O’Donovan,Katarzyna Piwocka,Sharon L. McKenna +4 more
TL;DR: Curcumin can induce cell death by a mechanism that is not reliant on apoptosis induction, and thus represents a promising anticancer agent for prevention and treatment of oesophageal cancer.
Journal ArticleDOI
A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells.
Katarzyna Piwocka,Krzysztof Zabłocki,Mariusz R. Wieckowski,Janusz Skierski,Izabella Feiga,Jan Szopa,Nadzieja Drela,Lech Wojtczak,Ewa Sikora +8 more
TL;DR: It is concluded that the programmed cell death induced by curcumin in Jurkat cells differs from "classical" by the lack of mitochondrial depolarization and of the involvement of caspases.
Journal ArticleDOI
Inhibition of proliferation and apoptosis of human and rat T lymphocytes by curcumin, a curry pigment
TL;DR: The capacity of curcumin to inhibit both cell growth and death strongly implies that these two biological processes share a common pathway at some point and thatCurcumin affects a common step, presumably involving a modulation of the AP-1 transcription factor.
Journal ArticleDOI
Curcumin Affects Components of the Chromosomal Passenger Complex and Induces Mitotic Catastrophe in Apoptosis-Resistant Bcr-Abl-Expressing Cells
Kamila Wolanin,Adriana Magalska,Grazyna Mosieniak,Rut Klinger,Sharon L. McKenna,Susanne Vejda,Ewa Sikora,Katarzyna Piwocka +7 more
TL;DR: It is shown thatCurcumin can overcome the broad resistance to cell death caused by expression of Bcr-Abl and suggests that curcumin may be a promising agent for new combination regimens for drug-resistant chronic myeloid leukemia.