Kate E. Keller

TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: Modeling exercises support substantial impairment in outflow facility with increased HTM stiffness, and suggest an increased flow resistance with increasing HTM modulus in the onset and progression of glaucoma.

TL;DR: This review summarizes the current literature on trabecular ECM as well as the development and function of the TM and the growing number of mutations that have been identified in ECM genes and genes that modulate ECM in humans with glaucoma are documented.

TL;DR: Recently identified podosome- or invadopodia-like structures (PILS) may aid in the focal degradation of ECM and organization of replacement components.