K
Katherine Holland
Researcher at University of Cambridge
Publications - 2
Citations - 147
Katherine Holland is an academic researcher from University of Cambridge. The author has contributed to research in topics: Expression quantitative trait loci & Microglia. The author has an hindex of 2, co-authored 2 publications receiving 37 citations.
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Journal ArticleDOI
A map of transcriptional heterogeneity and regulatory variation in human microglia.
Adam Young,Adam Young,Natsuhiko Kumasaka,Fiona Calvert,Timothy R. Hammond,Timothy R. Hammond,Andrew J Knights,Nikolaos Panousis,Jun Sung Park,Jeremy Schwartzentruber,Jimmy Z. Liu,Kousik Kundu,Michael Segel,Natalia A. Murphy,Christopher E McMurran,Harry Bulstrode,Jason Correia,Karol P. Budohoski,Alexis J Joannides,Mathew R. Guilfoyle,Rikin A. Trivedi,Ramez W. Kirollos,Robert H. Morris,Matthew R. Garnett,Ivan Timofeev,Ibrahim Jalloh,Katherine Holland,Richard Mannion,Richard Mair,Colin Watts,Stephen J. Price,Peter J. Kirkpatrick,Thomas Santarius,Edward Mountjoy,Maya Ghoussaini,Nicole Soranzo,Omer Ali Bayraktar,Beth Stevens,Beth Stevens,Peter J. Hutchinson,Robin J.M. Franklin,Daniel J. Gaffney +41 more
TL;DR: In this paper, gene expression variation in primary human microglia isolated from 141 patients undergoing neurosurgery was profiled using expression quantitative trait loci (eQTL) mapping.
Posted ContentDOI
A map of transcriptional heterogeneity and regulatory variation in human microglia
Adam Mh Young,Natsuhiko Kumasaka,Fiona Calvert,Timothy R. Hammond,Andrew J Knights,Nikolaos Panousis,Jeremy Schwartzentruber,Jimmy Z. Liu,Kousik Kundu,Michael Segel,Natalia A. Murphy,Christopher E McMurran,Harry Bulstrode,Jason Correia,Karol P. Budohoski,Alexis J Joannides,Mathew R. Guilfoyle,Rikin A. Trivedi,Ramez W. Kirollos,Robert H. Morris,Matthew R. Garnett,Helen M Fernandes,Ivan Timofeev,Ibrahim Jalloh,Katherine Holland,Richard Mannion,Richard Mair,Colin Watts,Stephen J. Price,Peter J. Kirkpatrick,Thomas Santarius,Nicole Soranzo,Beth Stevens,Peter J. Hutchinson,Robin J.M. Franklin,Daniel J. Gaffney +35 more
TL;DR: This study provides the first population-scale transcriptional map of a critically important cell for neurodegenerative disorders and fine-map candidate causal variants at risk loci for Alzheimer’s disease.