K
Kathryn Winglee
Researcher at University of Washington
Publications - 2
Citations - 645
Kathryn Winglee is an academic researcher from University of Washington. The author has contributed to research in topics: Drug resistance & Efflux. The author has an hindex of 2, co-authored 2 publications receiving 553 citations.
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Drug tolerance in replicating mycobacteria mediated by a macrophage-induced efflux mechanism.
Kristin N. Adams,Kevin K. Takaki,Lynn E. Connolly,Heather Wiedenhoft,Kathryn Winglee,Olivier Humbert,Paul H. Edelstein,Christine L. Cosma,Lalita Ramakrishnan +8 more
TL;DR: The existence of multidrug-tolerant organisms that arise within days of infection, are enriched in the replicating intracellular population, and are amplified and disseminated by the tuberculous granuloma are described.
Journal ArticleDOI
Evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish
TL;DR: A 16-h protocol spanning 22 d is described, in which zebrafish larvae are infected via the two primary injection sites, the hindbrain ventricle and caudal vein; this is followed by the high-throughput evaluation of pathogenesis and antimicrobial efficacy.