Katri Rosenthal-Aizman

TL;DR: A novel CPP, PepFect 6 (PF6), comprising the previously reported stearyl-TP10 peptide, having pH titratable trifluoromethylquinoline moieties covalently incorporated to facilitate endosomal release is presented, implying that the peptides, in addition to having utility for RNAi screens in vitro, displays therapeutic potential.

TL;DR: In this article, a new class of delivery vectors with high pharmaceutical potential, called cell-penetrating peptides (CPPs), were proposed. But the ability of these peptides to translocate through cell membranes can be limited.

TL;DR: Cell-penetrating peptide conjugation of MTX is a new way of increasing delivery, and thereby, the potency of already well-characterized therapeutic molecules into drug resistant tumour cells.

TL;DR: Results strongly indicate the formation of peptide nanotubes that assemble with one enantiomer in every second position, thereby forming a lamellar structure.

TL;DR: In this article, a novel homing peptide that recognizes tumor vessels and invasive tumor satellites in glioblastomas was identified, and the peptide-targeted delivery of chemotherapeutics prolonged the lifespan of mice bearing invasive brain tumors and significantly reduced the number of tumor satellites.