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Katrina M. Miranda
Researcher at University of Arizona
Publications - 105
Citations - 10871
Katrina M. Miranda is an academic researcher from University of Arizona. The author has contributed to research in topics: Nitroxyl & Nitric oxide. The author has an hindex of 48, co-authored 103 publications receiving 9970 citations. Previous affiliations of Katrina M. Miranda include National Institutes of Health & Johns Hopkins University.
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Journal ArticleDOI
A rapid, simple spectrophotometric method for simultaneous detection of nitrate and nitrite.
TL;DR: A method for simultaneous evaluation of nitrate and nitrite concentrations in a microtiter plate format is developed and S-Nitrosothiols and L-arginine derivatives were found to be potential interfering agents.
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Mechanisms of the antioxidant effects of nitric oxide.
David A. Wink,Katrina M. Miranda,Michael Graham Espey,Ryzard M. Pluta,Sandra J. Hewett,Carol A. Colton,Michael P. Vitek,Martin Feelisch,Mathew B. Grisham +8 more
TL;DR: The attenuation of metal/peroxide oxidative chemistry, as well as lipid peroxidation, appears to be the major chemical mechanisms by which NO may limit oxidative injury to mammalian cells.
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Positive inotropic and lusitropic effects of HNO/NO− in failing hearts: Independence from β-adrenergic signaling
Nazareno Paolocci,Tatsuo Katori,Hunter C. Champion,Marcus E. St. John,Katrina M. Miranda,Jon M. Fukuto,David A. Wink,David A. Kass +7 more
TL;DR: HNO/NO− has positive inotropic and lusitropic action, which unlike NO/nitrates is independent and additive to β-adrenergic stimulation and stimulates CGRP release, which suggests potential of HNO/ NO− donors for the treatment of heart failure.
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Nitric oxide-induced cellular stress and p53 activation in chronic inflammation.
Lorne J. Hofseth,Shin'ichi Saito,S. Perwez Hussain,Michael Graham Espey,Katrina M. Miranda,Yuzuru Araki,Chamelli Jhappan,Yuichiro Higashimoto,Peijun He,Steven P. Linke,Martha Quezado,Irit Zurer,Varda Rotter,David A. Wink,Ettore Appella,Curtis C. Harris +15 more
TL;DR: In noncancerous colon tissues from patients with ulcerative colitis, inducible NO synthase protein levels were positively correlated with p53 serine 15 phosphorylation levels, and Immunostaining of HDM-2 and p21WAF1 was consistent with transcriptionally active p53.
Journal ArticleDOI
The reduction potential of nitric oxide (NO) and its importance to NO biochemistry
Michael D. Bartberger,Wei Liu,Eleonora Ford,Katrina M. Miranda,Christopher H. Switzer,Jon M. Fukuto,Patrick J. Farmer,David A. Wink,Kendall N. Houk +8 more
TL;DR: Results represent a substantial revision of the derived and widely cited values of +0.39 V and −0.35 V for the NO/3NO− and NO/1NO− couples, respectively, and provide support for previous measurements obtained by electrochemical and photoelectrochemical means.