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Katsumi Higaki

Researcher at Tottori University

Publications -  117
Citations -  9125

Katsumi Higaki is an academic researcher from Tottori University. The author has contributed to research in topics: Chemical chaperone & Endoplasmic reticulum. The author has an hindex of 34, co-authored 110 publications receiving 8275 citations. Previous affiliations of Katsumi Higaki include Columbia University.

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Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Chemical chaperone therapy for brain pathology in GM1-gangliosidosis

Junichiro Matsuda, +19 more
- 23 Dec 2003 - 
TL;DR: A galactose derivative synthesized for chemical chaperone therapy of a human neurogenetic disease, β-galactosidosis, resulted in significant enhancement of the enzyme activity in the brain and other tissues and a marked decrease of intracellular substrate storage.
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Complete Genetic Correction of iPS Cells From Duchenne Muscular Dystrophy

Yasuhiro Kazuki, +15 more
- 01 Feb 2010 - 
TL;DR: The complete correction of a genetic deficiency in iPS cells derived from Duchenne muscular dystrophy model mice and a human DMD patient is shown using a HAC with a complete genomic dystrophin sequence (DYS-HAC).
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Niemann-Pick Disease Type C: Spectrum of HE1 Mutations and Genotype/Phenotype Correlations in the NPC2 Group

Gilles Millat, +8 more
- 01 Nov 2001 - 
TL;DR: The first comprehensive study of eight unrelated families with NPC2, originating from France, Algeria, Italy, Germany, the Czech Republic, and Turkey, is reported, with a remarkable feature was the pronounced lung involvement, leading, in six patients, to early death caused by respiratory failure.
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Ambroxol chaperone therapy for neuronopathic Gaucher disease: A pilot study.

Aya Narita, +26 more
- 02 Feb 2016 - 
TL;DR: Evaluated the safety, tolerability, and neurological efficacy of ambroxol in patients with neuronopathic GD to offer a new strategy for treating the neurological manifestations of this disease.