K
Katsumori Segawa
Researcher at Osaka University
Publications - 39
Citations - 6741
Katsumori Segawa is an academic researcher from Osaka University. The author has contributed to research in topics: Phosphatidylserine & Flippase. The author has an hindex of 23, co-authored 35 publications receiving 5875 citations. Previous affiliations of Katsumori Segawa include Kyoto University.
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Journal ArticleDOI
Visfatin: a protein secreted by visceral fat that mimics the effects of insulin.
Atsunori Fukuhara,Morihiro Matsuda,Masako Nishizawa,Katsumori Segawa,Masaki Tanaka,Kae Kishimoto,Yasushi Matsuki,Mirei Murakami,Tomoko Ichisaka,Hiroko Murakami,Eijiro Watanabe,Toshiyuki Takagi,Megumi Akiyoshi,Tsuguteru Ohtsubo,Shinji Kihara,Shizuya Yamashita,Makoto Makishima,Tohru Funahashi,Shinya Yamanaka,Ryuji Hiramatsu,Yuji Matsuzawa,Iichiro Shimomura,Iichiro Shimomura +22 more
TL;DR: A newly identified adipocytokine, visfatin, that is highly enriched in the visceral fat of both humans and mice and whose expression level in plasma increases during the development of obesity is isolated.
Journal ArticleDOI
Adipose Tissue Hypoxia in Obesity and Its Impact on Adipocytokine Dysregulation
Naomi Hosogai,Atsunori Fukuhara,Kazuya Oshima,Yugo Miyata,Sachiyo Tanaka,Katsumori Segawa,Shigetada Furukawa,Yoshihiro Tochino,Ryutaro Komuro,Morihiro Matsuda,Iichiro Shimomura +10 more
TL;DR: It is shown that adipose tissue of obese mice is hypoxic and that local adipose tissues hypoxia dysregulates the production of adipocytokines, and the results suggest that hypoperfusion and Hypoxia in adipose organs underlie the dysregulated production of fat-derived secretory factors and metabolic syndrome in obesity.
Journal ArticleDOI
Visfatin : A protein secreted by visceral fat that mimics the effects of insulin
Atsunori Fukuhara,Morihiro Matsuda,Masako Nishizawa,Katsumori Segawa,Masaki Tanaka,Kae Kishimoto,Yasushi Matsuki,Mirei Murakami,Tomoko Ichisaka,Hiroko Murakami,Eijoro Watanabe,Toshiyuki Takagi,Megumi Akiyoshi,Tsuguteru Ohtsubo,Shinji Kiliara,Shizuya Yamashita,Makoto Makishima,Tohru Funahashi,Shinya Yamanaka,Ryuji Hiramatsu,Yuji Matsuzawa,Iichiro Shimomura +21 more
TL;DR: A newly identified adipocytokine, visfatin, that is highly enriched in the visceral fat of both humans and mice and whose expression level in plasma increases during the development of obesity is isolated.
Journal ArticleDOI
An Apoptotic ‘Eat Me’ Signal: Phosphatidylserine Exposure
TL;DR: Recent findings regarding the molecular mechanisms of apoptosis PtdSer exposure and the clearance of apoptotic cells are discussed.
Journal ArticleDOI
Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure
Katsumori Segawa,Sachiko Kurata,Yuichi Yanagihashi,Thijn R. Brummelkamp,Fumihiko Matsuda,Shigekazu Nagata +5 more
TL;DR: Using a haploid genetic screen in human cells, it is found that ATP11C and CDC50A are required for aminophospholipid translocation from the outer to the inner plasma membrane leaflet; that is, they display flippase activity.