K
Kazuyoshi Tsutsui
Researcher at Waseda University
Publications - 354
Citations - 19573
Kazuyoshi Tsutsui is an academic researcher from Waseda University. The author has contributed to research in topics: Hypothalamus & Neuroactive steroid. The author has an hindex of 74, co-authored 347 publications receiving 18050 citations. Previous affiliations of Kazuyoshi Tsutsui include Rashtrasant Tukadoji Maharaj Nagpur University & Hiroshima University.
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Journal ArticleDOI
A novel avian hypothalamic peptide inhibiting gonadotropin release.
Kazuyoshi Tsutsui,Etsuko Saigoh,Kazuyoshi Ukena,Hitoshi Teranishi,Yuko Fujisawa,Motoshi Kikuchi,Susumu Ishii,Peter J. Sharp +7 more
TL;DR: It is shown, in a bird, that the hypothalamus also contains a novel peptide which inhibits gonadotropin release, the first hypothalamic peptide inhibiting gonadotropic hormone reported in a vertebrate.
Journal ArticleDOI
Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals
Lance J. Kriegsfeld,Dan Feng Mei,George E. Bentley,Takayoshi Ubuka,Alex O. Mason,Kazuhiko Inoue,Kazuyoshi Ukena,Kazuyoshi Tsutsui,Rae Silver +8 more
TL;DR: The distribution of GnIH efferents to neural sites regulating reproductive behavior and neuroendocrine secretions, expression of steroid receptors in GnIh-ir nuclei, and GnI H inhibition of luteinizing hormone secretion indicate the discovery of a system regulating the mammalian reproductive axis.
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Rat RFamide-related peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat
TL;DR: Results indicate that although RFRP-3 has similar effects on LH as observed with GnIH in avian species, in the rat RFRPs has additional roles in regulating feeding and growth.
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Salt-sensitive hypertension in circadian clock-deficient Cry-null mice involves dysregulated adrenal Hsd3b6.
Masao Doi,Yukari Takahashi,Rie Komatsu,Fumiyoshi Yamazaki,Hiroyuki Yamada,Shogo Haraguchi,Noriaki Emoto,Yasushi Okuno,Gozoh Tsujimoto,Akihiro Kanematsu,Osamu Ogawa,Takeshi Todo,Kazuyoshi Tsutsui,Gijsbertus T. J. van der Horst,Hitoshi Okamura +14 more
TL;DR: Type VI 3β-hydroxyl-steroid dehydrogenase (Hsd3b6) is identified as a new hypertension risk factor in mice and placed in a pivotal position through which circadian clock malfunction is coupled to the development of hypertension.
Journal ArticleDOI
Neurosteroid biosynthesis: enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides.
Jean Luc Do Rego,Jean Luc Do Rego,Jae Young Seong,Delphine Burel,Delphine Burel,Jérôme Leprince,Jérôme Leprince,Van Luu-The,Kazuyoshi Tsutsui,Marie Christine Tonon,Marie Christine Tonon,Georges Pelletier,Hubert Vaudry +12 more
TL;DR: The observation that the activity of key steroidogenic enzymes is finely tuned by various neurotransmitters and neuropeptides strongly suggests that some of the central effects of these neuromodulators may be mediated via the regulation of neurosteroid production.