Author
Keiichiro Fukumoto
Bio: Keiichiro Fukumoto is an academic researcher from Tohoku University. The author has contributed to research in topics: Total synthesis & Enantioselective synthesis. The author has an hindex of 19, co-authored 184 publications receiving 1278 citations.
Papers published on a yearly basis
Papers
More filters
TL;DR: In this article, a concise and practical route to the enantiomerically pure des-A B-trienic steroid was developed by thermolysis of the optically active alkenic benzocyclobutene 13 obtained by selective nucleophilic addition of isopropenyl group to the chiral epoxide 9 as a key step.
Abstract: A concise and practical route to the enantiomerically pure des-A B-trienic steroid 14 was developed by thermolysis of the optically active alkenic benzocyclobutene 13 obtained by selective nucleophilic addition of isopropenyl group to the chiral epoxide 9 as a key step.
6 citations
TL;DR: This paper showed that trimethylsilyl iodide in the presence of hexamethyldisilazane caused sequential three reactions, ring opening of cyclopropane-Michael-aldol reaction sequence, to provide polycyclic cyclobutane derivatives.
6 citations
6 citations
TL;DR: Optically active des-A C-13 ethyl steroids 17∼20 have been synthesized by thermolysis of the optically active alkenic benzocyclobutene 14 as a key process as discussed by the authors.
Abstract: Optically active des-A C-13 ethyl steroids 17∼20 have been synthesized by thermolysis of the optically active alkenic benzocyclobutene 14 as a key process.
6 citations
TL;DR: In this paper, an intramolecular aldol reaction of keto acetals was performed with Me3SiI−(Me3Si)2NH====== leading to spirobicyclic compounds.
Abstract: An intramolecular aldol reaction of keto acetals 1, regioselectively
performed with Me3SiI–(Me3Si)2NH
leading to spirobicyclic compounds 2 and 3, has been applied to the
syntheses of (±)-spirojatamol and
(±)-erythrodiene.
6 citations
Cited by
More filters
TL;DR: This review covers the isolation, structure determination, synthesis and biological activity of quinoline, quinazoline and acridone alkaloids from plant, microbial and animal sources.
1,687 citations
1,661 citations
TL;DR: The Diels-Alder reaction has both enabled and shaped the art and science of total synthesis over the last few decades to an extent which has yet to be eclipsed by any other transformation in the current synthetic repertoire as mentioned in this paper.
Abstract: The Diels-Alder reaction has both enabled and shaped the art and science of total synthesis over the last few decades to an extent which, arguably, has yet to be eclipsed by any other transformation in the current synthetic repertoire. With myriad applications of this magnificent pericyclic reaction, often as a crucial element in elegant and programmed cascade sequences facilitating complex molecule construction, the Diels-Alder cycloaddition has afforded numerous and unparalleled solutions to a diverse range of synthetic puzzles provided by nature in the form of natural products. In celebration of the 100th anniversary of Alder's birth, selected examples of the awesome power of the reaction he helped to discover are discussed in this review in the context of total synthesis to illustrate its overall versatility and underscore its vast potential which has yet to be fully realized.
1,427 citations
Book•
11 Sep 2006TL;DR: It is shown that domino reactions initiated by oxidation or reduction or reduction, as well as other mechanisms, can be inhibited by various materials, such as Na6(CO3)(SO4), Na2SO4, Na2CO3, and so on.
Abstract: Introduction Cationic domino reactions Anionic domino reactions Radical domino reactions Pericyclic domino reactions Photochemically induced domino processes Transition metal catalysis Domino reactions initiated by oxidation or reduction Enzymes in domino reactions Multicomponent reactions Special techniques in domino reactions
1,337 citations
763 citations