K
Keiichiro Fukumoto
Researcher at Tohoku University
Publications - 184
Citations - 1304
Keiichiro Fukumoto is an academic researcher from Tohoku University. The author has contributed to research in topics: Enantioselective synthesis & Intramolecular force. The author has an hindex of 19, co-authored 184 publications receiving 1278 citations.
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Journal ArticleDOI
1,2-Asymmetric induction in intramolecular Michael reaction. A novel and enantioselective route to (+)-Geissman lactone
TL;DR: The Horner-Emmons reaction of the hemiacetal (19), derived from L-(+)-diethyl tartrate, was found to give the pyrrolidine (21) via an intramolecular Michael reaction as a mixture of diastereoisomers which, after treatment with ethanethiol and boron trifluoride-diethy ether, was converted into the lactone (22) and the ester (23) as mentioned in this paper.
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Tandem Michael addition–[3,3]sigmatropic rearrangement processes. Part 2. Construction of cyclopropa[3,4]pyrrolo[3,2-e]indol-4-one (CPI) unit of antitumour antibiotic CC-1065
TL;DR: In this paper, an alternative strategy for preparing 3-acetoxymethyl-2,3-dihydro-1-methylsulfon-yl-6-methoxyindole 25 has been developed.
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The competition between electrocyclic reaction and [1,5]sigmatropic reaction in the thermolysis of 1,1-disubstituted benzocyclobutenes
TL;DR: In this article, 1-acyl-1-alkylbenzocyclobutenes was found to give predominantly the corresponding isochromenes via Z-conformer of the o-quinodimethane in the transition state.
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A novel and general route to diverse A-ring aromatic trichothecanes via cyclobutanes
TL;DR: In this article, a novel and generally applicable approach to A-ring aromatic trichothecane 2 was achieved by the regiocontrolled cyclization of 25, 26, 29, and 30 as a key step, followed by stereoselective construction of the epoxide ring.
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An asymmetric synthesis of benzylic quaternary carbon centers. A formal total synthesis of (−)-mesembrine
TL;DR: In this paper, the optically pure sulfone was converted into the olefinic cyclobutanone, which was then transformed into the ketonic lactone via the oleinic lactone.