K
Keith Mcdade
Publications - 11
Citations - 9552
Keith Mcdade is an academic researcher. The author has contributed to research in topics: Massive parallel sequencing & Oligonucleotide. The author has an hindex of 7, co-authored 10 publications receiving 9347 citations.
Papers
More filters
Journal ArticleDOI
Genome sequencing in microfabricated high-density picolitre reactors
Marcel Margulies,Michael Egholm,William E. Altman,Said Attiya,Joel S. Bader,Lisa A. Bemben,Jan Berka,Michael S. Braverman,Yi-Ju Chen,Zhoutao Chen,Scott Dewell,Lei Du,J. M. Fierro,Xavier V. Gomes,Brian C. Godwin,Wen He,Scott Edward Helgesen,Chun Heen Ho,Gerard P. Irzyk,Szilveszter C. Jando,Maria L. I. Alenquer,Thomas P. Jarvie,Kshama B. Jirage,Jong-Bum Kim,James R. Knight,Janna R. Lanza,John H. Leamon,Steven Lefkowitz,Ming Lei,Jing Li,Kenton Lohman,Hong Lu,Vinod Makhijani,Keith Mcdade,Michael P. McKenna,Eugene W. Myers,Elizabeth Nickerson,John Nobile,Ramona Plant,Bernard P. Puc,Michael T. Ronan,George T. Roth,Gary J. Sarkis,Jan Fredrik Simons,John Simpson,Maithreyan Srinivasan,Karrie R. Tartaro,Alexander Tomasz,Kari A. Vogt,Greg A. Volkmer,Shally H. Wang,Yong Wang,Michael P. Weiner,Pengguang Yu,Richard F. Begley,Jonathan M. Rothberg +55 more
TL;DR: A scalable, highly parallel sequencing system with raw throughput significantly greater than that of state-of-the-art capillary electrophoresis instruments with 96% coverage at 99.96% accuracy in one run of the machine is described.
Patent
Method of sequencing a nucleic acid
Jonathan M. Rothberg,Joel S. Bader,Scott Dewell,Keith Mcdade,John Simpson,Jan Berka,Christopher M. Colangelo +6 more
TL;DR: In this article, methods and apparatuses for sequencing a nucleic acid are presented. But their methods require a large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
Patent
Apparatus and method for sequencing a nucleic acid
Jonathan M. Rothberg,Joel S. Bader,Scott Dewell,Keith Mcdade,John Simpson,Jane Berka,Christopher M. Colangelo,Michael P. Weiner +7 more
TL;DR: In this article, methods and apparatuses for sequencing a nucleic acid are presented. But their methods require a large number of independent sequencing reactions to be arrayed in parallel, permitting simultaneous sequencing of a very large number (>10,000) of different oligonucleotides.
Patent
Methods of amplifying sequencing nucleic acids
Keith Mcdade,Joseph M. Fierro,James R. Knight,Jerry Charumilind,John H. Leamon,Eugene W. Myers,John W. Simpson,Greg A. Volkmer +7 more
TL;DR: In this paper, an apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is provided, which includes the steps of preparing a sample DNA for genomic sequencing and amplifying the prepared DNA in a representative manner.
Journal ArticleDOI
Correction: Corrigendum: Genome sequencing in microfabricated high-density picolitre reactors
Marcel Margulies,Michael Egholm,William E. Altman,Said Attiya,Joel S. Bader,Lisa A. Bemben,Jan Berka,Michael S. Braverman,Yi-Ju Chen,Zhoutao Chen,Scott Dewell,Alex de Winter,James Drake,Lei Du,J. M. Fierro,Robin Forte,Xavier V. Gomes,Brian C. Godwin,Wen He,Scott Edward Helgesen,Chun Heen Ho,Stephen K. Hutchison,Gerard P. Irzyk,Szilveszter C. Jando,Maria L. I. Alenquer,Thomas P. Jarvie,Kshama B. Jirage,Jong-Bum Kim,James R. Knight,Janna R. Lanza,John H. Leamon,William Lee,Steven Lefkowitz,Ming Lei,Jing Li,Kenton Lohman,Hong Lu,Vinod Makhijani,Keith Mcdade,Michael P. McKenna,Eugene W. Myers,Elizabeth Nickerson,John Nobile,Ramona Plant,Bernard P. Puc,Michael Reifler,Michael T. Ronan,George T. Roth,Gary J. Sarkis,Jan Fredrik Simons,John Simpson,Maithreyan Srinivasan,Karrie R. Tartaro,Alexander Tomasz,Kari A. Vogt,Greg A. Volkmer,Shally H. Wang,Yong Wang,Michael P. Weiner,David Willoughby,Pengguang Yu,Richard F. Begley,Jonathan M. Rothberg +62 more
TL;DR: This corrects the article to show that the Higgs boson bacterium is a prokaryotic substance, not a “spatially aggregating substance”, which is a type of “plague” found in the immune system.