K
Kelly A. Soderberg
Researcher at Duke University
Publications - 20
Citations - 4279
Kelly A. Soderberg is an academic researcher from Duke University. The author has contributed to research in topics: Antibody & Epitope. The author has an hindex of 14, co-authored 20 publications receiving 3896 citations. Previous affiliations of Kelly A. Soderberg include Durham University.
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Journal ArticleDOI
Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial
Barton F. Haynes,Peter B. Gilbert,M. Juliana McElrath,Susan Zolla-Pazner,Georgia D. Tomaras,S. Munir Alam,David T. Evans,David C. Montefiori,Chitraporn Karnasuta,Ruengpueng Sutthent,Hua-Xin Liao,Anthony L. DeVico,George K. Lewis,Constance Williams,Abraham Pinter,Youyi Fong,Holly Janes,Allan C. deCamp,Yunda Huang,Mangala Rao,Erik Billings,Nicos Karasavvas,Merlin L. Robb,Viseth Ngauy,Mark de Souza,Robert Paris,Guido Ferrari,Robert T. Bailer,Kelly A. Soderberg,Charla Andrews,Phillip W. Berman,Nicole Frahm,Stephen C. De Rosa,Michael D. Alpert,Nicole L. Yates,Xiaoying Shen,Richard A. Koup,Punnee Pitisuttithum,Jaranit Kaewkungwal,Sorachai Nitayaphan,Supachai Rerks-Ngarm,Nelson L. Michael,Jerome H. Kim +42 more
TL;DR: V vaccines that are designed to induce higher levels of V1V2 antibodies and lower levels of Env-specific IgA antibodies than are induced by the RV144 vaccine may have improved efficacy against HIV-1 infection.
Journal ArticleDOI
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
Hua-Xin Liao,Rebecca M. Lynch,Tongqing Zhou,Feng Gao,Feng Gao,S. Munir Alam,S. Munir Alam,Scott D. Boyd,Andrew Fire,Krishna M. Roskin,Chaim A. Schramm,Zhenhai Zhang,Jiang Zhu,Lawrence Shapiro,Lawrence Shapiro,Nisc Comparative Sequencing Program,James C. Mullikin,Sandrasegaram Gnanakaran,Peter T. Hraber,Kevin Wiehe,Kevin Wiehe,Garnett Kelsoe,Garnett Kelsoe,Guang Yang,Guang Yang,Shi-Mao Xia,Shi-Mao Xia,David C. Montefiori,David C. Montefiori,Robert Parks,Robert Parks,Krissey E. Lloyd,Krissey E. Lloyd,Richard M. Scearce,Richard M. Scearce,Kelly A. Soderberg,Kelly A. Soderberg,Myron S. Cohen,Gift Kamanga,Mark K. Louder,Lillian Tran,Yue Chen,Yue Chen,Fangping Cai,Fangping Cai,Sheri Chen,Sheri Chen,Stephanie Moquin,Xiulian Du,M. Gordon Joyce,Sanjay Srivatsan,Baoshan Zhang,Anqi Zheng,George M. Shaw,Beatrice H. Hahn,Thomas B. Kepler,Bette T. Korber,Peter D. Kwong,John R. Mascola,Barton F. Haynes,Barton F. Haynes +60 more
TL;DR: The isolation, evolution and structure of a broadly neutralizing antibody from an African donor followed from the time of infection and its co-crystal structure revealed a new loop-based mechanism of CD4-binding-site recognition.
Journal ArticleDOI
Influence of HLA-C Expression Level on HIV Control
Richard Apps,Richard Apps,Ying Qi,Ying Qi,Jonathan M. Carlson,Haoyan Chen,Haoyan Chen,Xiaojiang Gao,Xiaojiang Gao,Rasmi Thomas,Yuko Yuki,Yuko Yuki,Greg Q. Del Prete,Philip J. R. Goulder,Philip J. R. Goulder,Philip J. R. Goulder,Zabrina L. Brumme,Chanson J. Brumme,Mina John,Simon Mallal,George W. Nelson,Ronald J. Bosch,David Heckerman,Judy L. Stein,Kelly A. Soderberg,M. Anthony Moody,Thomas N. Denny,Xue Zeng,Xue Zeng,Jingyuan Fang,Ashley Moffett,Jeffrey D. Lifson,James J. Goedert,Susan Buchbinder,Gregory D. Kirk,Jacques Fellay,Paul J. McLaren,Steven G. Deeks,Florencia Pereyra,Bruce D. Walker,Nelson L. Michael,Amy C. Weintrob,Steven M. Wolinsky,Wilson Liao,Mary Carrington,Mary Carrington +45 more
TL;DR: It is demonstrated that increasing surface expression of HLA-C is associated with reduced viral load and reduced rate of progression to low CD4+ T cell counts in African and European Americans.
Journal ArticleDOI
Vaccine-induced IgG antibodies to V1V2 regions of multiple HIV-1 subtypes correlate with decreased risk of HIV-1 infection
Susan Zolla-Pazner,Allan C. deCamp,Peter B. Gilbert,Constance Williams,Nicole L. Yates,William T. Williams,Robert Howington,Youyi Fong,Daryl E. Morris,Kelly A. Soderberg,Carmela Irene,Charles Reichman,Abraham Pinter,Robert Parks,Punnee Pitisuttithum,Jaranit Kaewkungwal,Supachai Rerks-Ngarm,Sorachai Nitayaphan,Charla Andrews,Robert J. O'Connell,Zhi Yong Yang,Gary J. Nabel,Jerome H. Kim,Nelson L. Michael,David C. Montefiori,Hua-Xin Liao,Barton F. Haynes,Georgia D. Tomaras +27 more
TL;DR: Levels of vaccine-induced IgG Abs recognizing V1V2 regions from multiple HIV-1 subtypes, and presented on different scaffolds constitute inverse correlates of risk for HIV- 1 infection in the RV144 vaccine trial.
Journal ArticleDOI
The development of CD4 binding site antibodies during HIV-1 infection.
Rebecca M. Lynch,Lillian Tran,Mark K. Louder,Stephen D. Schmidt,Myron S. Cohen,Rebecca DerSimonian,Zelda Euler,Elin S. Gray,Salim S. Abdool Karim,Jennifer L. Kirchherr,David C. Montefiori,Sengeziwe Sibeko,Kelly A. Soderberg,Georgia D. Tomaras,Zhi Yong Yang,Gary J. Nabel,Hanneke Schuitemaker,Lynn Morris,Barton F. Haynes,John R. Mascola +19 more
TL;DR: Improved understanding of the immunological factors associated with the development and maturation of neutralizing CD4bs antibodies during HIV-1 infection may provide insights into the requirements for eliciting this response by vaccination.