K
Kelton Tremellen
Researcher at Flinders University
Publications - 120
Citations - 7217
Kelton Tremellen is an academic researcher from Flinders University. The author has contributed to research in topics: Infertility & Pregnancy. The author has an hindex of 37, co-authored 108 publications receiving 6191 citations. Previous affiliations of Kelton Tremellen include Flinders Medical Centre & University of South Australia.
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Journal ArticleDOI
Oxidative stress and male infertility—a clinical perspective
TL;DR: This review will provide an overview of oxidative biochemistry related to sperm health and identify which men are most at risk of oxidative infertility, and outline methods available for diagnosing oxidative stress and the various treatments available.
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BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis
Nathalie Sermondade,Céline Faure,Léopold Fezeu,A G Shayeb,Jens Peter Bonde,Tina Kold Jensen,M. van Wely,Jan Tan Cao,A. C. Martini,M Eskandar,Jorge E. Chavarro,Jorge E. Chavarro,S Koloszar,John M. Twigt,Cecilia Høst Ramlau-Hansen,Edson Borges,Francesco Lotti,Régine P.M. Steegers-Theunissen,B Zorn,Alex J. Polotsky,S. La Vignera,Brenda Eskenazi,Kelton Tremellen,E V Magnusdottir,I Fejes,Serge Hercberg,Rachel Levy,Sébastien Czernichow +27 more
TL;DR: Overweight and obesity were associated with an increased prevalence of azoospermia or oligozoospermia, and whether weight normalization could improve sperm parameters should be evaluated further.
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Seminal Fluid Induces Leukocyte Recruitment and Cytokine and Chemokine mRNA Expression in the Human Cervix after Coitus
David J. Sharkey,Kelton Tremellen,Melinda J. Jasper,Kristina Gemzell-Danielsson,Sarah A. Robertson +4 more
TL;DR: The leukocyte and cytokine environment induced in the cervix by seminal fluid appears competent to initiate adaptations in the female immune response that promote fertility and is also relevant to transmission of sexually transmitted pathogens and potentially, susceptibility to cervical metaplasia.
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Primary unexplained infertility is associated with reduced expression of the T-regulatory cell transcription factor Foxp3 in endometrial tissue.
TL;DR: The finding of reduced endometrial Foxp3 implicates impaired differentiation of uterine T cells into the Treg phenotype as a key determinant of fertility in women.
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Seminal plasma differentially regulates inflammatory cytokine gene expression in human cervical and vaginal epithelial cells
TL;DR: It is shown that seminal plasma can elicit expression of a range of inflammatory cytokines and chemokines in reproductive tract epithelia, and implicate the ectocervix as the primary site of responsiveness, with gene-specific differences in the kinetics and site-restrictedness of the response.