K
Ken Ichirou Morohashi
Researcher at Kyushu University
Publications - 20
Citations - 2841
Ken Ichirou Morohashi is an academic researcher from Kyushu University. The author has contributed to research in topics: Steroidogenic factor 1 & Gene. The author has an hindex of 19, co-authored 20 publications receiving 2774 citations. Previous affiliations of Ken Ichirou Morohashi include Nara Medical University & National Institute for Basic Biology, Japan.
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Journal ArticleDOI
Ad4BP regulating steroidogenic P-450 gene is a member of steroid hormone receptor superfamily.
Shin-ichiro Honda,Ken Ichirou Morohashi,Masatoshi Nomura,Hiroyuki Takeya,Masato Kitajima,Tsuneo Omura +5 more
TL;DR: Comparison of the primary structures of the hormone receptor superfamily showed that Ad4BP was highly homologous to FTZ-F1, which regulates the fushi tarazu gene, and ELP, which is expressed in the murine embryonal carcinoma cells.
Journal ArticleDOI
Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz‐F1 disrupted mice
Koh Shinoda,Hong Lei,Hironori Yoshii,Masatoshi Nomura,Mamoru Nagano,Hiroharu Shiba,Hiroshi Sasaki,Yoshio Osawa,Yasuharu Ninomiya,Ohtsura Niwa,Ken Ichirou Morohashi,En Li +11 more
TL;DR: In this paper, double immunostaining of the pituitary for Ad4BP and trophic peptide hor- mones, FSH, TSH, and ACTH, indicated a re-stricted localization of the transcription factor to the gonadotroph.
Journal ArticleDOI
Identical origin of adrenal cortex and gonad revealed by expression profiles of Ad4BP/SF-1
TL;DR: Recent gene disruption studies with the mammalian Ftz‐F1 gene encoding Ad4BP/SF‐1 clearly revealed the essential function of the factor for adrenal and gonadal differentiation.
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Sex-dependent expression of a transcription factor, Ad4BP, regulating steroidogenic P-450 genes in the gonads during prenatal and postnatal rat development.
Osamu Hatano,Koichi Takayama,Tsuneo Imai,Michael R. Waterman,Akira Takakusu,Tsuneo Omura,Ken Ichirou Morohashi +6 more
TL;DR: It is suggested that the Müllerian inhibitory substance gene may be a target of Ad4BP since this gene has a conserved Ad4-binding site within the promoter, which is recognized by Ad4 BP expressed in the fetal testes.
Journal ArticleDOI
Ad4BP/SF-1 regulates cyclic AMP-induced transcription from the proximal promoter (PII) of the human aromatase P450 (CYP19) gene in the ovary
TL;DR: It is concluded that cAMP-stimulated transcription of human aromatase P450 in the ovary is due, at least in part, to increased levels and DNA binding activity of Ad4BP/SF-1.