Kenton Lohman

TL;DR: A scalable, highly parallel sequencing system with raw throughput significantly greater than that of state-of-the-art capillary electrophoresis instruments with 96% coverage at 99.96% accuracy in one run of the machine is described.

TL;DR: An apparatus and method for performing rapid DNA sequencing, such as genomic sequencing, is described in this paper, which includes the steps of preparing a sample DNA for sequencing, amplifying the prepared DNA in a representative manner, and performing multiple sequencing reaction on the amplified DNA with only one primer hybridization step.

TL;DR: In this paper, a method for nucleic acid amplification is described, in which the templates, beads, and amplification reaction solution are emulsified and the nucleic acids are amplified to provide clonal copies of the templates attached to the beads.

TL;DR: The PicoTiterPlate as discussed by the authors is a platform for simultaneous polymerase chain reaction (PCR) amplification of up to 300,000 discrete reactions in a novel platform, which can be performed in extremely small volumes: individual reactions volumes are as low as 39.5 pL, with a total 15.3 micro-L reaction volume for the entire platform.

TL;DR: In this paper, a pyrophosphate sequencing technique was proposed for SNP detection, classification, and assessment of individual allelic polymorphisms in one individual or a population of individuals, which can be used for diagnostic and treatment of patients as well as assessment of viral and bacterial population identification.