scispace - formally typeset
K

Kevin M. Coombs

Researcher at University of Manitoba

Publications -  118
Citations -  4380

Kevin M. Coombs is an academic researcher from University of Manitoba. The author has contributed to research in topics: Virus & Viral replication. The author has an hindex of 31, co-authored 110 publications receiving 3082 citations. Previous affiliations of Kevin M. Coombs include University of Texas at Austin & University of Wisconsin-Madison.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
Journal ArticleDOI

Early steps in reovirus infection are associated with dramatic changes in supramolecular structure and protein conformation: analysis of virions and subviral particles by cryoelectron microscopy and image reconstruction.

KA Dryden, +7 more
- 01 Sep 1993 - 
TL;DR: Three structural forms of type 1 Lang reovirus (virions, intermediate subviral particles [ISVPs], and cores) have been examined by cryoelectron microscopy and image reconstruction at 27 to 32-A resolution to reveal dramatic changes in supra-molecular structure and protein conformation that are related to the early steps of reov virus infection.
Journal ArticleDOI

Quantitative Proteomic Analyses of Influenza Virus-Infected Cultured Human Lung Cells

Kevin M. Coombs, +9 more
- 15 Oct 2010 - 
TL;DR: Gene ontology and pathway analyses indicated differentially regulated proteins and included those involved in host cell immunity and antigen presentation, cell adhesion, metabolism, protein function, signal transduction, and transcription pathways.
Journal ArticleDOI

The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections

Parvaneh Mehrbod, +10 more
- 30 Apr 2019 - 
TL;DR: This review article focuses upon how apoptosis, autophagy, and UPR are involved in the regulation of cellular responses to arboviruses, influenza virus and HIV infections.
Journal ArticleDOI

A comparative analysis of freon substitutes in the purification of reovirus and calicivirus.

Israel I Mendez, +3 more
- 01 Oct 2000 - 
TL;DR: Considerations of flammability and ease of use suggest that Vertrel XF is the preferred choice as a Freon substitute for the purification of these non-enveloped viruses.