Khadem Ali

TL;DR: Clinical and experimental evidence is reviewed that highlights the potential importance of iron in respiratory diseases and infections and increased understanding of the role that iron plays in the pathogenesis of lung disease and respiratory infections may help inform novel therapeutic strategies.

TL;DR: Experimental and clinical data demonstrate that increased accumulation of pulmonary iron plays a key role in the pathogenesis of pulmonary fibrosis and lung function decline and highlight the potential for the therapeutic targeting of increased pulmonary iron in the treatment of fibrotic lung diseases such as IPF.

TL;DR: It is shown for the first time that altered iron responses are a key feature of clinical and experimental asthma and may play important roles in disease.

TL;DR: The results suggest that the extract possesses significant analgesic, anti-inflammatory and anti-diarrheal activities that support to the ethnopharmacological uses of this plant.

TL;DR: A novel gradual de-PAB mouse model is established and used to demonstrate that established pulmonary hypertension-associated RV dysfunction is fully reversible, and links functional RV improvement to hypertrophic normalization that precedes fibrotic and vascular reverse-remodeling events.