K
Kinshuk Banerjee
Researcher at Bose Corporation
Publications - 45
Citations - 280
Kinshuk Banerjee is an academic researcher from Bose Corporation. The author has contributed to research in topics: Entropy production & Non-equilibrium thermodynamics. The author has an hindex of 7, co-authored 45 publications receiving 227 citations. Previous affiliations of Kinshuk Banerjee include University of Calcutta & Rice University.
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Elucidating interplay of speed and accuracy in biological error correction.
TL;DR: By analyzing the fundamental processes of DNA replication and protein translation, this work established that these systems maximize speed rather than accuracy with additional energetic constraints, and indicates that both speed and accuracy can be enhanced in certain parameter regimes.
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Heterogeneity of Stop Codon Readthrough in Single Bacterial Cells and Implications for Population Fitness
Yongqiang Fan,Christopher R. Evans,Karl W. Barber,Kinshuk Banerjee,Kalyn J. Weiss,William Margolin,Oleg A. Igoshin,Jesse Rinehart,Jiqiang Ling +8 more
TL;DR: The results indicate that fluctuations in the concentrations of translational components lead to UGA readthrough heterogeneity among single cells, which enhances phenotypic diversity of the genetically identical population and facilitates its adaptation to changing environments.
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Accuracy of Substrate Selection by Enzymes Is Controlled by Kinetic Discrimination
TL;DR: It is shown that the steady-state selectivity error is determined only by the differences in transition-state energies between the pathways and is independent of the energies of the stable complexes.
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Entropic estimate of cooperative binding of substrate on a single oligomeric enzyme: An index of cooperativity
TL;DR: An index of cooperativity, C, defined in terms of the ratio of the surprisals or equivalently, the stochastic system entropy associated with the fully bound state of the cooperative and non-cooperative cases is introduced.
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Metabolic stress promotes stop-codon readthrough and phenotypic heterogeneity.
Hong Zhang,Zhihui Lyu,Yongqiang Fan,Yongqiang Fan,Christopher R. Evans,Karl W. Barber,Kinshuk Banerjee,Oleg A. Igoshin,Jesse Rinehart,Jiqiang Ling +9 more
TL;DR: A metabolic stress caused by excess carbon substantially increases both the level and heterogeneity of stop-codon readthrough during protein synthesis in bacteria, revealing a metabolic stress that promotes translational heterogeneity and phenotypic diversity.